Description

2-Oxabicyclo[2.1.1]hexan-4-amine hydrochloride is a high-purity, advanced pharmaceutical intermediate featuring a unique strained bicyclic scaffold. This compound is of significant commercial interest for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in medicinal chemistry research. It is primarily sought after by pharmaceutical R&D laboratories, agrochemical innovators, and specialty chemical manufacturers developing next-generation therapeutics and fine chemicals.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, especially those targeting the central nervous system (CNS) and other therapeutic areas.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Agrochemical Synthesis: Serves as a building block for developing new crop protection agents and herbicides with novel modes of action.
• Chemical Biology Probes: Utilized in the development of molecular probes to study enzyme function and biological pathways.
• Ligand and Catalyst Development: Acts as a precursor for chiral ligands or organocatalysts used in asymmetric synthesis.
• Academic & Industrial R&D: Employed in fundamental research exploring new chemical spaces and reactivity of strained heterocycles.

Basic Information

Product Name	2-Oxabicyclo[2.1.1]hexan-4-amine hydrochloride
CAS No.	2260936-52-3
Molecular Formula	C5H10ClNO
Molecular Weight	135.59 g/mol
Synonyms	4-Amino-2-oxabicyclo[2.1.1]hexane hydrochloride; 2-Oxabicyclo[2.1.1]hexan-4-amine, hydrochloride; 2-Oxa-4-aminobicyclo[2.1.1]hexane HCl; 1-Amino-3-oxabicyclo[3.1.0]hexane hydrochloride (alternative numbering); Bicyclo[2.1.1]hexan-4-amine, 2-oxa-, hydrochloride
EINECS	Contact for details

Quality Control

Our 2-Oxabicyclo[2.1.1]hexan-4-amine hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere or in a desiccator after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.