Description

(S)-1-(5-Bromo-4-Methylpyridin-2-Yl)Ethanamine Dihydrochloride is a high-purity chiral amine building block, specifically the dihydrochloride salt of a substituted pyridine derivative. This compound is a critical intermediate for the synthesis of novel active pharmaceutical ingredients (APIs) and advanced organic materials. It is primarily utilized by research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries for creating targeted molecules with specific stereochemistry.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) and oncology targets.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides where the specific stereochemistry can influence biological activity.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Research: Employed as a building block for probes and tool compounds to study biological pathways and protein interactions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects.
• Academic Research: Used in university and institutional labs for methodological development and novel compound library synthesis.

Basic Information

Product Name	(S)-1-(5-Bromo-4-Methylpyridin-2-Yl)Ethanamine Dihydrochloride
CAS No.	2250243-78-6
Molecular Formula	C8H12BrN2·2HCl
Molecular Weight	312.01 g/mol (free base: 215.10 g/mol)
Synonyms	(S)-1-(5-Bromo-4-methylpyridin-2-yl)ethan-1-amine dihydrochloride; (S)-1-(5-Bromo-4-methyl-2-pyridinyl)ethylamine dihydrochloride; (S)-α-Methyl-5-bromo-4-methyl-2-pyridineethanamine dihydrochloride; (S)-5-Bromo-4-methyl-2-(1-aminoethyl)pyridine dihydrochloride; (S)-2-(1-Aminoethyl)-5-bromo-4-methylpyridine dihydrochloride; (S)-1-(5-Bromo-4-methyl-2-pyridyl)ethylamine dihydrochloride
EINECS	Contact for details

Quality Control

Our (S)-1-(5-Bromo-4-Methylpyridin-2-Yl)Ethanamine Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This material is hygroscopic (moisture-sensitive) and should be handled under dry, inert conditions to maintain stability and purity. Allow the container to reach ambient temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.