Description

(2S)-2-({[(9H-Fluoren-9-Yl)Methoxy]Carbonyl}Amino)-6-{Methyl[(Prop-2-En-1-Yloxy)Carbonyl]Amino}Hexanoic Acid is a sophisticated, multi-functional amino acid derivative designed for advanced chemical synthesis. This compound is a critical building block in solid-phase peptide synthesis (SPPS), where it provides orthogonal protection for the lysine side chain, enabling the construction of complex peptides and bioconjugates. It is essential for researchers and manufacturers in pharmaceutical development, proteomics, and the production of therapeutic peptides and antibody-drug conjugates (ADCs).

Application

• Solid-Phase Peptide Synthesis (SPPS): Serves as a key Fmoc-protected amino acid building block with an Alloc-protected side chain for orthogonal deprotection strategies.
• Pharmaceutical Intermediates: Used in the research and development of novel peptide-based therapeutics and active pharmaceutical ingredients (APIs).
• Bioconjugation: Facilitates the site-specific modification of proteins, antibodies, and other biomolecules to create antibody-drug conjugates (ADCs) and diagnostic probes.
• Combinatorial Chemistry: Employed in the generation of diverse peptide libraries for drug discovery and high-throughput screening.
• Proteomics Research: Acts as a tool compound for studying protein-protein interactions and post-translational modifications.
• Material Science: Potential use in the synthesis of peptide-based polymers and smart biomaterials.

Basic Information

Product Name	(2S)-2-({[(9H-Fluoren-9-Yl)Methoxy]Carbonyl}Amino)-6-{Methyl[(Prop-2-En-1-Yloxy)Carbonyl]Amino}Hexanoic Acid
CAS No.	2246708-86-9
Molecular Formula	C26H28N2O6
Molecular Weight	464.51 g/mol
Synonyms	Fmoc-Lys(Alloc)-OH; Fmoc-Lys(Alloc)-OH; Nα-Fmoc-Nε-Alloc-L-lysine; Fmoc-Lys(Alloc)-OH; (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-6-((allyloxy)carbonyl)(methyl)amino)hexanoic acid; Fmoc-Lys(Alloc)-OH; Nα-Fmoc-Nε-Alloc-L-lysine; Fmoc-L-lysine(N-Alloc) derivative
EINECS	Contact for details

Quality Control

Our (2S)-2-({[(9H-Fluoren-9-Yl)Methoxy]Carbonyl}Amino)-6-{Methyl[(Prop-2-En-1-Yloxy)Carbonyl]Amino}Hexanoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and chiral integrity suitable for sensitive pharmaceutical and research applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C in a dry, cool place. This product is hygroscopic (moisture-sensitive) and light-sensitive; prolonged exposure to ambient conditions or light may affect stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residual Solvents	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.