Description

3,5-Bis(Pyridin-4-Ylethynyl)Benzoic Acid is a high-purity, functionalized organic building block characterized by its extended conjugated structure and terminal carboxylic acid group. This compound matters for its role as a critical precursor in advanced materials science and pharmaceutical research, enabling the synthesis of complex molecular architectures. It is primarily needed by R&D chemists and process engineers in the fields of organic electronics, metal-organic frameworks (MOFs), and medicinal chemistry for developing novel functional materials and active pharmaceutical ingredients (APIs).

Application

• Organic Semiconductor Precursor: Serves as a key monomer or dopant for constructing conjugated polymers and small molecules used in OLEDs, OFETs, and photovoltaic cells.
• Ligand for Metal-Organic Frameworks (MOFs): The rigid, linear structure and multiple coordination sites make it an excellent ligand for designing porous MOFs with tailored properties for gas storage, separation, and catalysis.
• Pharmaceutical Intermediate: Used in the synthesis of complex drug candidates, particularly those targeting neurological disorders or cancers, where the pyridine and benzoic acid motifs are pharmacologically relevant.
• Fluorescent Probe & Sensor Development: The extended π-conjugation system is ideal for creating highly sensitive fluorescent probes and chemosensors for detecting metal ions or biological molecules.
• Cross-coupling Reactions: Acts as a sophisticated substrate in Sonogashira, Suzuki, and other palladium-catalyzed cross-coupling reactions to build complex, multi-aryl structures.
• Surface Functionalization Agent: Used to modify nanoparticles, graphene, or other nanomaterials to impart specific electronic or binding properties.

Basic Information

Item	Detail
Product Name	3,5-Bis(Pyridin-4-Ylethynyl)Benzoic Acid
CAS No.	2243148-99-2
Molecular Formula	C21H12N2O2
Molecular Weight	324.34 g/mol
Synonyms	3,5-Bis(4-pyridylethynyl)benzoic acid; 4,4'-(5-Carboxy-1,3-phenylene)bis(ethyne-2,1-diyl)dipyridine; Benzoic acid, 3,5-bis(4-pyridinylethynyl)-; 3,5-Di(4-pyridylethynyl)benzoic acid; 3,5-Bis[(4-pyridinyl)ethynyl]benzoic acid; 3,5-BPEBA
EINECS	Contact for details

Quality Control

Every batch of 3,5-Bis(Pyridin-4-Ylethynyl)Benzoic Acid undergoes rigorous analytical testing to ensure it meets the high-purity standards required for research and development. Our quality assurance protocol includes multiple orthogonal techniques such as HPLC, NMR, and mass spectrometry for definitive identification and purity verification. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment to guarantee traceability and compliance with your internal specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture uptake, which can affect purity and stability. For long-term storage, consider storing under an inert atmosphere such as argon or nitrogen.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.