Description

(S)-2-(2-((S)-(4-(tert-Butyl)Phenyl)Sulfinyl)Phenyl)-4-Phenyl-4,5-Dihydrooxazole is a high-purity, chiral oxazoline ligand with a sulfinyl group, offering a sophisticated molecular architecture for asymmetric synthesis. This compound is valued for its role as a key building block and ligand in the development of novel pharmaceuticals and advanced materials, where precise stereochemical control is paramount. It is primarily sought by research and development teams in the pharmaceutical, agrochemical, and fine chemical industries for applications in catalysis and as a chiral auxiliary.

Application

• As a chiral ligand in transition metal-catalyzed asymmetric reactions, such as hydrogenation, allylic substitution, and cyclopropanation.
• As a chiral auxiliary or resolving agent in the synthesis of enantiomerically pure active pharmaceutical ingredients (APIs).
• In the research and development of novel catalysts for stereoselective organic transformations.
• As a key intermediate in the synthesis of complex molecules for agrochemical and material science applications.
• For use in academic and industrial research focused on expanding the toolbox of asymmetric synthesis methodologies.

Basic Information

Product Name	(S)-2-(2-((S)-(4-(tert-Butyl)Phenyl)Sulfinyl)Phenyl)-4-Phenyl-4,5-Dihydrooxazole
CAS No.	2242702-44-7
Molecular Formula	C25H25NO2S
Molecular Weight	403.54 g/mol
Synonyms	(S,S)-tert-Butylsulfinyl Oxazoline Ligand; (S)-2-[2-[(S)-(4-tert-Butylphenyl)sulfinyl]phenyl]-4-phenyl-4,5-dihydrooxazole; (S,S)-tBu-SulfinylPHOX; Chiral Sulfinyl Oxazoline; Asymmetric Sulfinyl-Oxazoline Ligand; (S,S)-4,5-Dihydro-2-[2-[(S)-(4-tert-butylphenyl)sulfinyl]phenyl]-4-phenyloxazole; (S,S)-tBu-SO-PHOX
EINECS	Contact for details

Quality Control

Our (S)-2-(2-((S)-(4-(tert-Butyl)Phenyl)Sulfinyl)Phenyl)-4-Phenyl-4,5-Dihydrooxazole is manufactured under strict quality management systems to ensure batch-to-batch consistency and high chemical purity. Each lot is subjected to comprehensive analytical testing, including chiral HPLC for enantiomeric excess (ee) verification. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and other critical specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.