Description

trans-3-Methylcyclobutan-1-Amine Hydrochloride is a high-purity, chiral amine hydrochloride salt, a key building block in advanced organic synthesis. Its rigid cyclobutane structure and defined stereochemistry make it a valuable intermediate for constructing complex molecules with specific three-dimensional architectures. This compound is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, where precise molecular control is critical.

Application

• Pharmaceutical Intermediate: Serves as a chiral synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) and metabolic disease targets.
• Agrochemical Synthesis: Used in the creation of novel herbicides, fungicides, and insecticides that require specific stereochemistry for optimal activity.
• Ligand and Catalyst Development: Acts as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Chemical Biology Research: Employed as a molecular scaffold or probe in the study of biological pathways and protein interactions.
• Material Science: Potential building block for specialty polymers and advanced materials with unique thermal or mechanical properties.

Basic Information

Product Name	trans-3-Methylcyclobutan-1-Amine Hydrochloride
CAS No.	2231666-45-6
Molecular Formula	C5H12ClN
Molecular Weight	121.61 g/mol
Synonyms	(1R,3S)-3-Methylcyclobutan-1-amine hydrochloride; (1S,3R)-3-Methylcyclobutan-1-amine hydrochloride; trans-3-Methylcyclobutanamine hydrochloride; 3-Methylcyclobutan-1-amine hydrochloride (trans-); 3-Methylcyclobutanamine HCl; Cyclobutanamine, 3-methyl-, hydrochloride, trans-; 2231666-45-6
EINECS	Contact for details

Quality Control

Our trans-3-Methylcyclobutan-1-Amine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets the stringent requirements for research and process development. A detailed Certificate of Analysis (COA) providing specifications for identity, purity, and related substances is supplied with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% de
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.