Description

(2S,3R)-3-Fluoro-2-Methylazetidine Hydrochloride CAS NO 2231664-15-4 is a high-purity, chiral azetidine derivative used as a critical building block in advanced pharmaceutical synthesis. This compound is valued for its unique stereochemistry and fluorine substitution, which are essential for modulating the biological activity, metabolic stability, and physicochemical properties of novel drug candidates. It is primarily sought by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, particularly in areas requiring sophisticated small-molecule scaffolds.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs).
• Medicinal Chemistry: Used in structure-activity relationship (SAR) studies to explore novel bioactive molecules, especially in CNS and oncology research.
• Proteolysis Targeting Chimera (PROTAC) Development: Serves as a component in the linker or ligand design for targeted protein degradation platforms.
• Agrochemical Research: Potential intermediate for creating novel pesticides and herbicides with enhanced efficacy and selectivity.
• Fluorine Chemistry: A valuable substrate for further fluorination or functionalization reactions in synthetic chemistry.
• Ligand and Catalyst Development: Can be utilized to create chiral ligands for asymmetric catalysis.

Basic Information

Product Name	(2S,3R)-3-Fluoro-2-Methylazetidine Hydrochloride
CAS No.	2231664-15-4
Molecular Formula	C4H9ClFN
Molecular Weight	125.57 g/mol
Synonyms	(2S,3R)-3-Fluoro-2-methylazetidine hydrochloride; 3-Fluoro-2-methylazetidine hydrochloride, (2S,3R)-; Azetidine, 3-fluoro-2-methyl-, hydrochloride, (2S,3R)-; (2S,3R)-3-Fluoro-2-methylazetidine HCl; 3-Fluoro-2-methylazetidine HCl; (2S,3R)-3-Fluoro-2-methyl-azetidine hydrochloride
EINECS	Contact for details

Quality Control

Our (2S,3R)-3-Fluoro-2-Methylazetidine Hydrochloride is manufactured under strict quality control protocols to ensure high chemical and chiral purity suitable for research and development applications. Each batch is analyzed using advanced chromatographic and spectroscopic techniques. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere or in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.