Description

(trans-4-Ethynylcyclohexyl)Methanol is a versatile and highly functionalized organic building block featuring both a terminal alkyne and a primary alcohol group on a rigid cyclohexane scaffold. This unique bifunctional structure makes it a critical intermediate for the synthesis of complex molecules in advanced research and development. It is particularly valuable for industries focused on pharmaceutical discovery, agrochemical development, and the creation of novel materials, where its reactive handles enable efficient coupling and derivatization strategies.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the development of active pharmaceutical ingredients (APIs), particularly for constructing rigid molecular frameworks via Sonogashira or click chemistry.
• Agrochemical Synthesis: Used in the research and production of advanced crop protection agents and herbicides, leveraging its structural properties for bioactivity.
• Liquid Crystal & OLED Materials: Acts as a precursor for synthesizing advanced organic electronic materials, where the cyclohexyl core contributes to thermal stability and mesogenic properties.
• Polymer & Resin Modifier: Employed to introduce alkyne functionality into polymer backbones or cross-linking agents for creating specialty polymers with tailored properties.
• Chemical Biology & Probe Development: Utilized in bioconjugation and as a building block for fluorescent probes or PROTACs (Proteolysis Targeting Chimeras) due to its click-compatible alkyne group.
• Academic & Contract Research: A valuable reagent for synthetic organic chemists in academia and CROs (Contract Research Organizations) exploring new synthetic methodologies.

Basic Information

Product Name	(trans-4-Ethynylcyclohexyl)Methanol
CAS No.	2230789-49-6
Molecular Formula	C9H14O
Molecular Weight	138.21 g/mol
Synonyms	trans-4-Ethynylcyclohexanemethanol; 4-Ethynylcyclohexylmethanol (trans-); (trans-4-Ethynyl-1-cyclohexyl)methanol; 1-(trans-4-Ethynylcyclohexyl)methanol; 4-Ethynylcyclohexanecarbinol; (4-Ethynylcyclohexyl)methanol, trans-; 4-Ethynylcyclohexylcarbinol
EINECS	Contact for details

Quality Control

Our (trans-4-Ethynylcyclohexyl)Methanol is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and FTIR, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications. We support cGMP and ISO 9001 standards for manufacturing, ensuring reliability for critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5% w/w
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.