Description

Palladium, [butylbis(tricyclo[3.3.1.13,7]dec-1-yl)phosphine](methanesulfonato-κo)[2'-(methylamino-κn)[1,1'-biphenyl]-2-yl-κc]- is a sophisticated organometallic complex featuring a Buchwald-type ligand system. This compound is a highly active and selective catalyst designed for challenging cross-coupling reactions in advanced organic synthesis. It is essential for R&D chemists and process engineers in the pharmaceutical, agrochemical, and fine chemical industries who require reliable, high-performance catalysts for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate Synthesis: A key catalyst for Buchwald-Hartwig amination and related C-N, C-O, and C-C cross-coupling reactions to create active pharmaceutical ingredients (APIs).
• Agrochemical Manufacturing: Enables the synthesis of complex, nitrogen-containing heterocycles and other advanced intermediates for novel crop protection agents.
• Fine Chemical & Specialty Material Production: Used in the synthesis of ligands, OLED materials, and other high-value, performance chemicals.
• Academic & Industrial R&D: A critical tool for methodological development and exploring new chemical spaces in catalysis and synthetic chemistry.
• Scale-up Process Development: Suitable for optimizing and transferring robust catalytic processes from laboratory to pilot and production scale.

Basic Information

Product Name	Palladium, [butylbis(tricyclo[3.3.1.13,7]dec-1-yl)phosphine](methanesulfonato-κo)[2'-(methylamino-κn)[1,1'-biphenyl]-2-yl-κc]-
CAS No.	2230788-67-5
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Buchwald Palladacycle Precatalyst; Palladium(II) Methanesulfonate Complex with tBuBrettPhos and Biaryl Amine; tBuBrettPhos Palladacycle; Pd(tBuBrettPhos)(Amine)OMs Complex; Palladium G4 Catalyst Analog; BrettPhos-based Palladium Catalyst; (tBuBrettPhos)Pd(amine)OMs; Palladium Complex with 2-(Di-tert-butylphosphino)-3,6-dimethoxy-2',4',6'-triisopropyl-1,1'-biphenyl (tBuBrettPhos) and 2-(Methylamino)biphenyl
EINECS	Contact for details

Quality Control

Our high-value catalyst products are manufactured and handled under strict quality-controlled, inert environments to ensure activity and purity. Each batch is characterized using advanced analytical techniques, including NMR and HPLC, to confirm identity and assess critical impurity profiles. Certificates of Analysis (COA) detailing lot-specific data are provided with every shipment. We support compliance with cGMP and ICH guidelines for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at 2-8°C or as specified on the label. This material is easily oxidized and light-sensitive; prolonged exposure to air, moisture, or ambient light will degrade catalytic performance. The original sealed vial should be brought to room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	Yellow to orange solid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥95% (Area %)
Pd Content (ICP-MS)	Reported on COA
Solubility	Soluble in common organic solvents (e.g., THF, DCM, Toluene)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.