Description

(2-Dicyclohexylphosphino-1,1′-Biphenyl)[2-(2′-Amino-1,1′-Biphenyl)]Palladium(II) Methanesulfonate is a highly specialized, air-stable palladium catalyst pre-catalyst, widely recognized for its superior performance in cross-coupling reactions. This compound is valued for its exceptional reactivity and selectivity, enabling efficient synthesis of complex organic molecules under mild conditions. It is an essential tool for research and development in pharmaceutical chemistry, agrochemical synthesis, and advanced material science, where reliable and high-yielding catalytic processes are critical.

Application

• Pharmaceutical Intermediate Synthesis: A key catalyst for Buchwald-Hartwig amination, Suzuki-Miyaura, and other C-N, C-O, and C-C cross-coupling reactions in API development.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, and insecticides requiring complex aryl-amine or aryl-ether linkages.
• Material Science & OLED Development: Facilitates the construction of conjugated polymers and organic electronic materials for displays and lighting.
• Academic & Industrial R&D: A preferred pre-catalyst for method development and scale-up studies due to its stability and ease of handling.
• Fine Chemical Manufacturing: Enables the production of specialty chemicals, flavors, and fragrances with high selectivity.

Basic Information

Product Name	(2-Dicyclohexylphosphino-1,1′-Biphenyl)[2-(2′-Amino-1,1′-Biphenyl)]Palladium(II) Methanesulfonate
CAS No.	2230788-64-2
Molecular Formula	C₄₃H₅₀NO₃P₂PdS
Molecular Weight	876.27 g/mol
Synonyms	BrettPhos Pd G3 Methanesulfonate; [2-(2-Aminobiphenyl)]Pd(BrettPhos) Methanesulfonate; Pd-PEPPSI-IPent Methanesulfonate Analog; Palladium(II) (2-Dicyclohexylphosphino-3,6-dimethoxy-2',4',6'-triisopropyl-1,1'-biphenyl)(2-(2'-amino-1,1'-biphenyl)) Methanesulfonate; Pd(BrettPhos)(AmPhos) Methanesulfonate; (BrettPhos)Pd(AmPhos) OMs; Air-Stable Pd Precatalyst with BrettPhos and Amine Ligand.
EINECS	Contact for details

Quality Control

Our (2-Dicyclohexylphosphino-1,1′-Biphenyl)[2-(2′-Amino-1,1′-Biphenyl)]Palladium(II) Methanesulfonate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for sensitive catalytic applications. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at 2-8°C in a cool, dry place. This material is both hygroscopic (moisture-sensitive) and easily oxidized; prolonged exposure to air and moisture will degrade performance. Allow the sealed container to reach room temperature before opening to minimize condensation.

Specification

Item	Specification
Appearance	Yellow to orange-brown crystalline powder
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Pd Content	Contact for details
Solubility	Soluble in common organic solvents (DCM, THF, Toluene)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.