Description

[(1,3,5,7-Tetramethyl-6-Phenyl-2,4,6-Trioxa-6-Phosphaadamantane)-2-(2′-Amino-1,1′-Biphenyl)]Palladium(Ii) Methanesulfonate is a highly specialized, air-stable palladium catalyst complex designed for demanding cross-coupling reactions. Its value lies in the unique phosphine ligand architecture, which provides exceptional stability and reactivity, enabling efficient synthesis under mild conditions. This product is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-performance catalysts for constructing complex molecular frameworks. The compound is supplied with CAS number 2230788-58-4.

Application

This palladium catalyst is engineered for precision in synthetic organic chemistry, particularly where standard catalysts fail due to sensitivity or low activity.

• Pharmaceutical Intermediate Synthesis: Key for Suzuki-Miyaura, Buchwald-Hartwig, and other C–N/C–C cross-coupling reactions in API development.
• Agrochemical Research: Facilitating the construction of complex heterocycles and novel active ingredients.
• Materials Science: Catalyzing polymerizations and the synthesis of conjugated organic materials for electronics.
• Process Chemistry & Scale-up: Offers robust performance suitable for transitioning from laboratory to pilot plant scale.
• Academic & Industrial R&D: A premium tool for methodological development and exploring new reaction pathways.

Basic Information

Item	Details
Product Name	[(1,3,5,7-Tetramethyl-6-Phenyl-2,4,6-Trioxa-6-Phosphaadamantane)-2-(2′-Amino-1,1′-Biphenyl)]Palladium(Ii) Methanesulfonate
CAS No.	2230788-58-4
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Buchwald Palladacycle Methanesulfonate; G3-Pd Methanesulfonate; [(t-Bu)PhCg-Biph]Pd(OMs); Third-Generation Buchwald Precatalyst (Mesylate); Pd-PEPPSI-IPent(OMs) Analog; Air-Stable Palladacycle Catalyst; Methanesulfonic Acid Palladium Complex; Palladium(II) Methanesulfonate Catalyst
EINECS	Contact for details

Quality Control

Our production adheres to strict quality management protocols to ensure batch-to-batch consistency and high catalytic activity. Every lot is characterized using advanced analytical techniques including NMR, HPLC, and elemental analysis. A comprehensive Certificate of Analysis (COA) detailing purity, residual solvent content, and metal impurities is provided with each shipment. We support compliance with cGMP and ICH Q7 guidelines for applications in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at 2-8°C to maintain long-term stability and prevent oxidation and decomposition. Allow the sealed container to equilibrate to room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Palladium Content	Contact for details
Residual Solvents (GC)	Meets ICH limits

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.