Description

(2,2-Dimethyl-1-(4-(Trifluoromethoxy)Phenyl)Cyclopropyl)Methanol is a high-value, advanced pharmaceutical intermediate characterized by its unique cyclopropyl and trifluoromethoxy aromatic structure. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring specific stereochemistry and metabolic stability. It is primarily sought after by R&D and production teams in the pharmaceutical, agrochemical, and specialty chemical industries for developing next-generation small molecule drugs and crop protection agents.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel APIs targeting central nervous system (CNS) disorders, anti-inflammatory agents, and antiviral drugs.
• Agrochemical Synthesis: Serves as a precursor for developing advanced pesticides and herbicides, leveraging the stability imparted by the cyclopropyl and trifluoromethoxy groups.
• Chemical Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Ligand & Catalyst Preparation: Potential use in the preparation of chiral ligands or organocatalysts for asymmetric synthesis.
• Material Science: Intermediate for synthesizing specialty monomers or polymers with unique optical or electronic properties.

Basic Information

Product Name	(2,2-Dimethyl-1-(4-(Trifluoromethoxy)Phenyl)Cyclopropyl)Methanol
CAS No.	2228876-15-9
Molecular Formula	C13H15F3O2
Molecular Weight	260.26 g/mol
Synonyms	4-(Trifluoromethoxy)benzenecyclopropanemethanol, 2,2-dimethyl-; 1-(4-(Trifluoromethoxy)phenyl)-2,2-dimethylcyclopropanemethanol; α-(2,2-Dimethylcyclopropyl)-4-(trifluoromethoxy)benzenemethanol; (2,2-Dimethyl-1-(4-(trifluoromethoxyphenyl)cyclopropyl)methanol; (1R,2S)-rel-2,2-Dimethyl-1-[4-(trifluoromethoxy)phenyl]cyclopropanemethanol (if stereospecific)
EINECS	Contact for details

Quality Control

Our (2,2-Dimethyl-1-(4-(Trifluoromethoxy)Phenyl)Cyclopropyl)Methanol is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical synthesis steps.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Specific Rotation (if chiral)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.