Description

2-Oxabicyclo[2.1.1]hexane-1-carboxylic acid is a specialized bicyclic organic acid derivative, serving as a high-value synthetic intermediate in advanced chemical synthesis. Its unique strained oxabicyclic structure makes it a critical building block for constructing complex molecular architectures, particularly in pharmaceutical research and development. This compound is essential for medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors seeking novel scaffolds and chiral precursors.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), especially for central nervous system (CNS) and anti-infective drug candidates.
• Agrochemical Synthesis: Building block for developing new generation herbicides and fungicides with unique modes of action.
• Ligand and Catalyst Development: Used in the preparation of chiral ligands and organocatalysts for asymmetric synthesis.
• Polymer & Material Science: Monomer for creating specialty polymers with tailored thermal and mechanical properties.
• Chemical Biology Probes: Scaffold for designing molecular probes and tools to study enzyme function and biological pathways.
• Academic & Contract Research: Enables exploratory chemistry in academic institutions and contract research organizations (CROs) for novel compound libraries.

Basic Information

Product Name	2-Oxabicyclo[2.1.1]hexane-1-carboxylic Acid
CAS No.	2228699-81-6
Molecular Formula	C6H8O3
Molecular Weight	128.13 g/mol
Synonyms	1-Carboxy-2-oxabicyclo[2.1.1]hexane; Bicyclo[2.1.1]hexane-1-carboxylic acid, 2-oxa-; 2-Oxa-1-bicyclo[2.1.1]hexanecarboxylic acid; Oxabicyclohexanecarboxylic acid; OBCA; 2-Oxabicyclo[2.1.1]hexane-1-carboxylate
EINECS	Contact for details

Quality Control

Our production of 2-Oxabicyclo[2.1.1]hexane-1-carboxylic acid adheres to stringent quality management protocols to ensure batch-to-batch consistency and reliability for critical R&D and scale-up processes. Each lot is fully characterized and tested against comprehensive specifications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment. We support compliance with ICH Q7 guidelines and can tailor quality standards to meet specific customer requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and organic solvents. For long-term storage, consider inert atmosphere conditions to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C
Water Content (KF)	≤ 0.5% w/w

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.