Description

2-(2-Cyanophenyl)Cyclopropane-1-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate featuring a unique cyclopropane ring fused with a cyanophenyl moiety. This compound is valued for its role as a critical building block in the synthesis of complex, biologically active molecules, particularly in medicinal chemistry. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel therapeutic agents, including potential candidates for central nervous system (CNS) and anti-inflammatory applications.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) and investigational new drugs.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new drug candidates.
• Organic Synthesis Building Block: Employed in constructing complex molecular architectures, leveraging its reactive carboxylic acid and nitrile functional groups.
• Agrochemical Research: Potential intermediate in the development of novel pesticides or herbicides with specific activity profiles.
• Material Science: Investigated as a monomer or precursor for specialty polymers and advanced organic materials.

Basic Information

Product Name	2-(2-Cyanophenyl)Cyclopropane-1-Carboxylic Acid
CAS No.	2227758-80-5
Molecular Formula	C11H9NO2
Molecular Weight	187.20 g/mol
Synonyms	2-(2-Cyanophenyl)cyclopropanecarboxylic acid; 2-Cyanophenylcyclopropanecarboxylic Acid; Cyclopropanecarboxylic acid, 2-(2-cyanophenyl)-; 2-(2-CN-Ph)-cyclopropane-1-carboxylic acid; (1R,2S)-rel-2-(2-Cyanophenyl)cyclopropanecarboxylic Acid (for stereoisomers); 2-(2-Cyanophenyl)-1-cyclopropanecarboxylic Acid
EINECS	Contact for details

Quality Control

Our 2-(2-Cyanophenyl)Cyclopropane-1-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and development purposes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and away from moisture and direct light exposure to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.