Description

5-Bromo-8-Chloroquinoxaline is a high-purity, multi-functional heterocyclic building block essential for advanced organic synthesis. This compound is valued for its unique halogenated quinoxaline core, which enables precise molecular modifications in the development of complex chemical entities. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the creation of novel herbicides, fungicides, and pesticides, leveraging its halogenated structure for bioactivity.
• Material Science Research: Serves as a precursor for organic electronic materials, such as ligands for OLEDs and conductive polymers.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological pathways and enzyme functions.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed reactions like Suzuki, Stille, and Buchwald-Hartwig amination, enabling complex molecular assembly.
• Ligand Synthesis: Used to prepare novel chelating ligands for catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	5-Bromo-8-Chloroquinoxaline
CAS No.	2227206-68-8
Molecular Formula	C8H4BrClN2
Molecular Weight	243.49 g/mol
Synonyms	8-Chloro-5-bromoquinoxaline; Quinoxaline, 5-bromo-8-chloro-; 5-Bromo-8-chloro-quinoxaline; 5-Br-8-Cl-Quinoxaline; 8-Chloro-5-bromo-quinoxaline; 5-Bromo-8-chloroquinoxaline (CAS 2227206-68-8)
EINECS	Contact for details

Quality Control

Our 5-Bromo-8-Chloroquinoxaline is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials. The compound is light-sensitive and should be stored away from direct light exposure.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Maximum Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.