Description

3-(Difluoromethyl)-3-Methylazetidine Hydrochloride is a high-value azetidine-based building block, specifically designed for advanced pharmaceutical and agrochemical research. Its unique structure, featuring a difluoromethyl group, is critical for modulating the physicochemical and metabolic properties of target molecules. This compound is essential for medicinal chemists and process development scientists working on novel active ingredients, particularly in the areas of drug discovery and crop protection.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel drug candidates, especially for central nervous system (CNS) and anti-infective therapeutics.
• Agrochemical Research: Used in the development of next-generation herbicides, fungicides, and insecticides, where the difluoromethyl group enhances bioavailability and stability.
• Chemical Biology Probe Synthesis: Serves as a versatile scaffold for creating molecular probes to study enzyme function and biological pathways.
• Ligand and Catalyst Development: Employed in the design of novel chiral ligands and organocatalysts for asymmetric synthesis.
• Material Science Precursor: Potential use in the synthesis of specialty polymers and advanced materials with tailored properties.

Basic Information

Product Name	3-(Difluoromethyl)-3-Methylazetidine Hydrochloride
CAS No.	2227206-51-9
Molecular Formula	C6H12ClF2N
Molecular Weight	171.62 g/mol
Synonyms	3-Methyl-3-(difluoromethyl)azetidine hydrochloride; 3-(Difluoromethyl)-3-methylazetidine HCl; 3-Methyl-3-difluoromethylazetidine hydrochloride; Azetidine, 3-(difluoromethyl)-3-methyl-, hydrochloride (1:1); 2227206-51-9
EINECS	Contact for details

Quality Control

Every batch of 3-(Difluoromethyl)-3-Methylazetidine Hydrochloride is manufactured under strict quality management systems. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and development. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere or in a desiccator after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.