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T-Boc-Aminooxy-Peg7-Amine CAS NO 2226611-29-4


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CAS No.:2226611-29-4

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

T-Boc-Aminooxy-Peg7-Amine CAS NO 2226611-29-4 is a heterobifunctional polyethylene glycol (PEG) linker featuring a tert-butyloxycarbonyl (Boc)-protected aminooxy group and a primary amine terminus. This compound is engineered to facilitate the site-specific conjugation of biomolecules, offering a controlled and stable linkage crucial for advanced research and development. It is primarily utilized by scientists and manufacturers in the pharmaceutical and biotechnology sectors for applications such as antibody-drug conjugate (ADC) development, peptide modification, and the creation of diagnostic probes.

Application

  • Conjugation reagent for the site-specific modification of antibodies, proteins, and peptides.
  • Critical building block in the synthesis of Antibody-Drug Conjugates (ADCs) and other targeted therapeutics.
  • Linker for surface functionalization of nanoparticles and biomaterials to enhance biocompatibility and targeting.
  • Tool compound in bioconjugation chemistry for attaching payloads via oxime ligation.
  • Intermediate in the development of PEGylated drug candidates to improve pharmacokinetic properties.
  • Research reagent for creating fluorescent or affinity probes for diagnostic assays.

Basic Information

Product Name T-Boc-Aminooxy-Peg7-Amine
CAS No. 2226611-29-4
Molecular Formula C28H58N2O11
Molecular Weight 598.8 g/mol
Synonyms 1-Amino-3,6,9,12,15,18,21-heptaoxatricosan-23-yl (tert-butoxycarbonyl)aminooxycarbamate; Boc-NH-O-PEG7-NH2; tert-Butyl N-(23-amino-3,6,9,12,15,18,21-heptaoxatricos-23-yloxy)carbamate; Amino-PEG7-aminooxy, Boc-protected; Boc-Aminooxy-PEG7-amine; Heterobifunctional PEG linker, Boc-aminooxy/amine; 2,5,8,11,14,17,20-Heptaoxadocosan-22-yl (tert-butoxycarbonyl)aminooxycarbamate
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Quality Control

Our T-Boc-Aminooxy-Peg7-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided to support your research and cGMP development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a freezer at -20°C to -10°C under desiccant. This product is hygroscopic (moisture-sensitive). Allow the sealed vial to warm to room temperature before opening to minimize moisture condensation.

Specification

Item Specification
Appearance White to off-white solid or viscous oil
Identification (HPLC/MS) Conforms
Purity (HPLC) ≥ 95%
Water Content (KF) ≤ 1.0%
Molecular Weight Confirmation (MS) Conforms

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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