Description

(R)-(Tetrahydro-2H-Pyran-2-Yl)Methanamine Hydrochloride is a high-purity chiral amine hydrochloride salt, serving as a critical building block in advanced organic synthesis. Its value lies in providing a stereochemically defined scaffold for constructing complex molecules with high enantiomeric purity. This compound is essential for researchers and manufacturers in the pharmaceutical and fine chemical industries, particularly for developing active pharmaceutical ingredients (APIs) and novel agrochemicals.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the research and development of novel therapeutic agents, including central nervous system (CNS) drugs and enzyme inhibitors.
• Asymmetric Synthesis: Used as a chiral auxiliary or ligand precursor in catalytic asymmetric reactions to induce stereoselectivity.
• Agrochemical Research: Building block for creating enantiomerically pure pesticides and herbicides with improved efficacy and environmental profiles.
• Material Science: Potential monomer or modifier in the synthesis of specialty polymers and advanced functional materials.
• Academic & R&D: A valuable reagent for methodological studies in organic chemistry and medicinal chemistry programs.

Basic Information

Product Name	(R)-(Tetrahydro-2H-Pyran-2-Yl)Methanamine Hydrochloride
CAS No.	2202897-24-1
Molecular Formula	C6H14ClNO
Molecular Weight	151.63 g/mol
Synonyms	(R)-2-(Aminomethyl)tetrahydro-2H-pyran hydrochloride; (R)-Tetrahydro-2H-pyran-2-methanamine hydrochloride; (R)-THP-Methanamine HCl; (R)-(2-Tetrahydropyranyl)methylamine hydrochloride; (R)-Aminomethyltetrahydropyran hydrochloride; (R)-2-(Aminomethyl)oxane hydrochloride; (R)-THPMA-HCl
EINECS	Contact for details

Quality Control

Our (R)-(Tetrahydro-2H-Pyran-2-Yl)Methanamine Hydrochloride is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D and production. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.