Description

(S)-(5-Azaspiro[2.4]Heptan-6-Yl)Methanol Hydrochloride is a high-purity, chiral spirocyclic building block of significant interest in modern pharmaceutical research and development. This compound serves as a critical intermediate for the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders. It is essential for medicinal chemists and process development scientists in pharmaceutical and biotechnology companies who require advanced, stereochemically defined scaffolds to accelerate drug discovery pipelines.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new therapeutic agents.
• Medicinal Chemistry: Used in structure-activity relationship (SAR) studies and lead optimization for novel drug candidates.
• CNS Drug Discovery: Particularly valuable for synthesizing potential treatments for neurological and psychiatric conditions due to its spirocyclic azepane structure.
• Process Chemistry: Serves as a starting material or advanced intermediate in the scale-up and commercial route development for APIs.
• Asymmetric Synthesis: Employed in chiral pool synthesis to introduce complex, three-dimensional stereochemistry into target molecules.
• Chemical Biology: Can be utilized as a molecular probe or ligand in the study of biological targets and mechanisms.

Basic Information

Product Name	(S)-(5-Azaspiro[2.4]Heptan-6-Yl)Methanol Hydrochloride
CAS No.	2200258-97-3
Molecular Formula	C7H14ClNO
Molecular Weight	163.65 g/mol
Synonyms	(S)-6-(Hydroxymethyl)-5-azaspiro[2.4]heptane hydrochloride; (6S)-5-Azaspiro[2.4]heptan-6-ylmethanol hydrochloride; (S)-5-Azaspiro[2.4]heptane-6-methanol hydrochloride; (S)-6-(Hydroxymethyl)-5-azaspiro[2.4]heptane HCl; Azaspiroheptane methanol hydrochloride, (S)-; UNII-7J8J3V7A4P (component); (S)-enantiomer of 5-azaspiro[2.4]heptane-6-methanol HCl
EINECS	Contact for details

Quality Control

Our (S)-(5-Azaspiro[2.4]Heptan-6-Yl)Methanol Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with exacting standards for pharmaceutical R&D. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.