Description

Methanesulfonato[Di-T-Butyl(n-Butyl)Phosphine](2'-Amino-1,1'-Biphenyl-2-Yl)Palladium(II) Dichloromethane Adduct is a highly specialized, pre-activated palladium catalyst complex designed for efficient cross-coupling reactions. This compound matters because it offers superior catalytic activity and stability, streamlining synthesis workflows in advanced chemical manufacturing. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing complex molecular architectures. The product is supplied as a dichloromethane adduct to enhance its handling and shelf-life.

Application

• Pharmaceutical Intermediate Synthesis: A key catalyst for Buchwald-Hartwig amination and Suzuki-Miyaura cross-coupling reactions in API development.
• Agrochemical Research: Used in the synthesis of novel active ingredients requiring C-N and C-C bond formation.
• Materials Science: Facilitates the creation of conjugated polymers and organic electronic materials through efficient coupling protocols.
• Process Chemistry Optimization: Employed for scaling up coupling reactions from lab to pilot plant due to its consistent performance.
• Academic & Industrial R&D: A valuable tool for methodological development in synthetic organic chemistry.
• Fine Chemical Production: Enables the manufacture of complex, high-value specialty chemicals.

Basic Information

Product Name	Methanesulfonato[Di-T-Butyl(n-Butyl)Phosphine](2'-Amino-1,1'-Biphenyl-2-Yl)Palladium(II) Dichloromethane Adduct
CAS No.	2195390-27-1
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Palladium(II) Methanesulfonate Adduct; [(2'-Amino[1,1'-biphenyl]-2-yl)]Pd Complex; Buchwald-Hartwig Catalyst Precursor; Pd(dtbpb)(amphos)OMs·CH2Cl2; Di-tert-Butyl(n-butyl)phosphine Palladium Complex; (2-Aminobiphenyl-2-yl)palladium methanesulfonate adduct; Palladium G4 Catalyst derivative; AMPd Precursor
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Every batch is characterized to confirm identity, purity, and catalytic performance. Certificates of Analysis (COA) detailing assay, residual solvent content, and trace metal analysis are available upon request. We adhere to strict in-process controls to guarantee batch-to-batch consistency for your critical research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C to maintain stability and prevent decomposition. The container should be kept in a cool, dry, and well-ventilated area, away from incompatible materials. Allow the sealed container to reach room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	Orange to brown solid or crystalline powder
Identification (IR)	Conforms to structure
Assay (Pd content)	≥ 98.0% (by ICP-OES)
Purity (HPLC)	≥ 95.0%
Residual Solvents (GC)	Meets ICH guidelines
Trace Metals (ICP-MS)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.