Description

6-Quinolinecarbonitrile, 3-Fluoro- CAS NO 2177258-32-9 is a high-purity fluorinated quinoline derivative, a critical building block in modern synthetic chemistry. Its value lies in its unique molecular structure, which combines the versatile quinoline scaffold with a fluorine atom and a reactive nitrile group, enabling precise modifications for advanced material and pharmaceutical development. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries seeking to develop novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Research: Used in the development of new-generation pesticides and herbicides, where the fluorine atom enhances biological activity and environmental stability.
• Ligand & Catalyst Synthesis: Acts as a versatile starting material for creating specialized ligands and organocatalysts used in asymmetric synthesis and cross-coupling reactions.
• Functional Material Development: Employed in the research of organic electronic materials, such as OLEDs and semiconductors, due to the electron-deficient quinoline core.
• Chemical Biology Probe: Utilized to build molecular probes for studying enzyme function and biological pathways in diagnostic research.
• Custom Synthesis & Scale-up: A fundamental substrate for contract research organizations (CROs) and CDMOs offering custom synthesis services from milligram to kilogram scale.

Basic Information

Product Name	6-Quinolinecarbonitrile, 3-Fluoro-
CAS No.	2177258-32-9
Molecular Formula	C10H5FN2
Molecular Weight	172.16 g/mol
Synonyms	3-Fluoro-6-quinolinecarbonitrile; 3-Fluoroquinoline-6-carbonitrile; 6-Cyano-3-fluoroquinoline; 3-Fluoro-6-cyanoquinoline; Quinoline-6-carbonitrile, 3-fluoro-; 2177258-32-9; 3-Fluoroquinoline-6-CN
EINECS	Contact for details

Quality Control

Every batch of 6-Quinolinecarbonitrile, 3-Fluoro- is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and batch-to-batch consistency, meeting the stringent requirements of research and development. Certificates of Analysis (COA) with full analytical data are provided and can be tailored to meet specific customer or regulatory standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.