Description

Rel-(2R,4S)-1,2-Dimethylpiperidin-4-Amine Dihydrochloride is a high-purity, stereochemically defined chiral amine salt, serving as a critical building block in advanced organic synthesis. Its defined stereochemistry and salt form provide enhanced stability and handling properties, making it a valuable intermediate for the development of complex molecules. This compound is primarily sought after by pharmaceutical research and development teams, agrochemical innovators, and specialty chemical manufacturers for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) and other therapeutic areas.
• Agrochemical Synthesis: Used in the production of advanced crop protection agents and pesticides requiring specific stereochemistry for optimal activity.
• Catalyst Ligand Precursor: Serves as a starting material for synthesizing chiral ligands used in asymmetric catalysis.
• Fine Chemical Production: Employed in the manufacture of complex, high-value specialty chemicals for various industrial applications.
• Academic & Contract Research: Utilized in university and CRO laboratories for methodological development and exploratory synthesis projects.

Basic Information

Product Name	Rel-(2R,4S)-1,2-Dimethylpiperidin-4-Amine Dihydrochloride
CAS No.	2174980-90-4
Molecular Formula	C7H18N2 • 2HCl
Molecular Weight	223.15 g/mol (free base: 128.23 g/mol)
Synonyms	(2R,4S)-1,2-Dimethyl-4-aminopiperidine Dihydrochloride; 1,2-Dimethyl-4-aminopiperidine Dihydrochloride (rel-(2R,4S)-); 4-Amino-1,2-dimethylpiperidine Dihydrochloride; rel-(2R,4S)-1,2-Dimethylpiperidin-4-amine Dihydrochloride; 1,2-Dimethylpiperidin-4-amine Dihydrochloride; CAS 2174980-90-4
EINECS	Contact for details

Quality Control

Our Rel-(2R,4S)-1,2-Dimethylpiperidin-4-Amine Dihydrochloride is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification and impurity profiling, to ensure it meets the stringent requirements for advanced synthetic applications. A Certificate of Analysis (COA) detailing identity, purity (typically >97% by HPLC), chiral excess, and related substances is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.