Description

Sodium Quinazoline-5-Carboxylate is the sodium salt derivative of a quinazoline-based carboxylic acid, representing a high-value pharmaceutical intermediate and research chemical. This compound is critical for the synthesis of advanced drug candidates, particularly in oncology and targeted therapy research, due to its role as a key building block. It is essential for R&D laboratories, pharmaceutical manufacturers, and fine chemical synthesis units focused on developing novel small-molecule therapeutics.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of novel quinazoline-based active pharmaceutical ingredients (APIs).
• Oncology Drug Discovery: Used in research and development of targeted cancer therapies, including kinase inhibitors.
• Biochemical Research: Employed as a standard or reagent in enzymatic and receptor binding studies.
• Fine Chemical Synthesis: Acts as a specialized building block for constructing complex heterocyclic compounds in medicinal chemistry.
• Process Development: Utilized in scaling up and optimizing synthetic routes for GMP-grade material production.

Basic Information

Product Name	Sodium Quinazoline-5-Carboxylate
CAS No.	2173991-82-5
Molecular Formula	C9H5N2NaO2
Molecular Weight	196.14 g/mol
Synonyms	5-Quinazolinecarboxylic acid, sodium salt; Quinazoline-5-carboxylic acid sodium salt; Sodium 5-quinazolinecarboxylate; 1,3-Naphthyridine-5-carboxylic acid, sodium salt; SQ5C; AURORA KA-25131; Sodium quinoline-5-carboxylate (common misnomer)
EINECS	Contact for details

Quality Control

Our Sodium Quinazoline-5-Carboxylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals. A detailed Certificate of Analysis (COA) is provided with every shipment, ensuring traceability and compliance with customer specifications and relevant industry guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.