Description

(1S,2S)-Rel-2-(2-Bromo-1,3-Thiazol-5-Yl)Cyclopropan-1-Amine Dihydrobromide is a high-purity, advanced pharmaceutical intermediate featuring a unique cyclopropane-thiazole scaffold. This compound is critical for medicinal chemistry research and development, particularly in the synthesis of novel bioactive molecules targeting challenging disease pathways. It is primarily sought by pharmaceutical R&D teams and fine chemical manufacturers engaged in the development of new therapeutic agents, including potential antivirals and enzyme inhibitors.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel active pharmaceutical ingredients (APIs) with potential antiviral, antibacterial, or neurological activity.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization campaigns due to its constrained cyclopropane ring and halogenated thiazole moiety.
• Protease Inhibitor Development: Serves as a core scaffold or precursor in the design of protease inhibitors, leveraging the amine functionality for key molecular interactions.
• Chemical Biology Probes: Utilized in the development of chemical probes for studying biological pathways and target validation in early-stage drug discovery.
• Custom Synthesis & Scale-Up: A critical starting material for contract research and manufacturing organizations (CROs/CMOs) providing custom synthesis services for clinical trial materials.
• Academic Research: Employed in university and institutional labs for fundamental research in organic synthesis methodology and heterocyclic chemistry.

Basic Information

Product Name	(1S,2S)-Rel-2-(2-Bromo-1,3-Thiazol-5-Yl)Cyclopropan-1-Amine Dihydrobromide
CAS No.	2173052-92-9
Molecular Formula	C6H8BrN2S • 2HBr
Molecular Weight	Contact for details
Synonyms	(1S,2S)-2-(2-Bromo-1,3-thiazol-5-yl)cyclopropan-1-amine dihydrobromide; rel-(1S,2S)-2-(2-Bromothiazol-5-yl)cyclopropan-1-amine hydrobromide (2:1); 2-(2-Bromo-1,3-thiazol-5-yl)cyclopropan-1-amine dihydrobromide (rel-(1S,2S)-); 5-[(1S,2S)-2-Aminocyclopropyl]-2-bromo-1,3-thiazole dihydrobromide; (1S,2S)-2-(2-Bromothiazol-5-yl)cyclopropanamine dihydrobromide; BTT-CPA Dihydrobromide; 2173052-92-9
EINECS	Contact for details

Quality Control

Our (1S,2S)-Rel-2-(2-Bromo-1,3-Thiazol-5-Yl)Cyclopropan-1-Amine Dihydrobromide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support development needs with GMP-compatible processes and documentation for advanced pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.