Description

2-(1H-1,2,4-Triazol-1-Yl) Terephthalic Acid is a high-value, functionalized aromatic dicarboxylic acid derivative that serves as a critical building block in advanced organic synthesis. This compound matters because it integrates the versatile 1,2,4-triazole heterocycle with a terephthalic acid backbone, enabling the creation of materials with tailored chemical and physical properties. It is primarily needed by research and development chemists and process engineers in the pharmaceutical, agrochemical, and specialty polymer industries for developing novel active ingredients and high-performance materials.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, oncology, and anti-infective therapies.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and plant growth regulators, where the triazole moiety can impart specific biological activity.
• Ligand for Metal-Organic Frameworks (MOFs): Acts as a functionalized organic linker in the construction of advanced MOFs for gas storage, separation, and heterogeneous catalysis applications.
• Specialty Polymer Monomer: Employed in the synthesis of polyamides, polyesters, and polyimides to introduce heterocyclic functionality, potentially enhancing thermal stability, chemical resistance, or optical properties.
• Organic Electronic Materials: Investigated as a component in the development of organic semiconductors, light-emitting diodes (OLEDs), or photovoltaic materials due to its conjugated structure.
• Chemical Research & Development: A versatile scaffold for medicinal chemistry and material science research, enabling structure-activity relationship (SAR) studies and the exploration of new chemical spaces.

Basic Information

Product Name	2-(1H-1,2,4-Triazol-1-Yl) Terephthalic Acid
CAS No.	2170848-14-1
Molecular Formula	C10H7N3O4
Molecular Weight	233.18 g/mol
Synonyms	2-(1H-1,2,4-Triazol-1-yl)benzene-1,4-dicarboxylic acid; 1,4-Benzenedicarboxylic acid, 2-(1H-1,2,4-triazol-1-yl)-; Terephthalic acid, 2-(1,2,4-triazol-1-yl)-; 2-(1,2,4-Triazol-1-yl)terephthalic acid
EINECS	Contact for details

Quality Control

Our 2-(1H-1,2,4-Triazol-1-Yl) Terephthalic Acid is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with key parameters including assay (HPLC), related substances, and residual solvents, supporting its use in research and regulated environments. Specifications can be aligned with customer requirements for specific R&D or scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong acids and incompatible materials such as strong oxidizing agents. The container should be kept tightly sealed in a dry environment to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.