Description

1H-Pyrrole-3-Carboxamide, 5-[(Z)-(5-Fluoro-1,2-Dihydro-2-Oxo-3H-Indol-3-Ylidene)Methyl]-n-(2-Hydroxyethyl)-2,4-Dimethyl- is a high-purity, structurally complex heterocyclic compound designed for advanced research and development. This specialized chemical serves as a critical building block or intermediate in the synthesis of novel pharmaceutical agents, particularly in oncology and targeted therapies. It is essential for medicinal chemists and process development scientists in the pharmaceutical and biotechnology industries who require reliable, high-quality intermediates for drug discovery programs.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel small-molecule drug candidates, especially those targeting specific kinase pathways or protein-protein interactions.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to optimize the potency and selectivity of lead compounds.
• Oncology Drug Development: Serves as a core scaffold for developing potential anti-cancer agents due to its indole and pyrrole-based structure.
• Process Chemistry & Scale-Up: Employed in route scouting and optimization for the commercial-scale manufacturing of active pharmaceutical ingredients (APIs).
• Biochemical Research: May be utilized as a tool compound or probe to study specific biological mechanisms and enzyme inhibition.
• Custom Synthesis: Acts as a starting material for the custom synthesis of more complex, target-specific molecules for client-directed R&D projects.

Basic Information

Product Name	1H-Pyrrole-3-Carboxamide, 5-[(Z)-(5-Fluoro-1,2-Dihydro-2-Oxo-3H-Indol-3-Ylidene)Methyl]-n-(2-Hydroxyethyl)-2,4-Dimethyl-
CAS No.	2170562-55-5
Molecular Formula	C₁₈H₂₀FN₃O₃
Molecular Weight	345.37 g/mol
Synonyms	5-[(Z)-(5-Fluoro-2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-N-(2-hydroxyethyl)-2,4-dimethyl-1H-pyrrole-3-carboxamide; (Z)-5-((5-Fluoro-2-oxoindolin-3-ylidene)methyl)-N-(2-hydroxyethyl)-2,4-dimethyl-1H-pyrrole-3-carboxamide; 5-((5-Fluoro-2-oxo-2,3-dihydro-1H-indol-3-ylidene)methyl)-N-(2-hydroxyethyl)-2,4-dimethyl-1H-pyrrole-3-carboxamide; Fluoro-indole-pyrrole carboxamide derivative; CAS 2170562-55-5
EINECS	Contact for details

Quality Control

Our 1H-Pyrrole-3-Carboxamide, 5-[(Z)-(5-Fluoro-1,2-Dihydro-2-Oxo-3H-Indol-3-Ylidene)Methyl]-n-(2-Hydroxyethyl)-2,4-Dimethyl- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis, to ensure it meets the exacting standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive); therefore, containers should be kept tightly sealed in a desiccated environment to maintain stability and purity.

Specification

Item	Specification
Appearance	Yellow to orange solid powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (IR)	Spectrum matches reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.