Description

1H-Pyrazole-3,5-Dicarboxylic Acid, 1-[(3,5-Dicarboxyphenyl)Methyl]- is a high-purity, multifunctional organic building block featuring a pyrazole core symmetrically substituted with carboxylic acid groups. This compound is valued for its role as a versatile ligand and precursor in advanced material synthesis and pharmaceutical research. It is primarily sought after by R&D chemists and process development scientists in the fields of metal-organic frameworks (MOFs), coordination chemistry, and medicinal chemistry for constructing complex molecular architectures.

Application

• Metal-Organic Framework (MOF) Synthesis: Serves as a polydentate organic linker for constructing porous coordination polymers with potential applications in gas storage, separation, and catalysis.
• Pharmaceutical Intermediate: Acts as a key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting enzymes where the pyrazole dicarboxylate moiety can act as a pharmacophore or binding group.
• Coordination Chemistry & Catalyst Design: Used as a chelating ligand to form stable complexes with various metal ions, which can be employed in homogeneous catalysis or as functional materials.
• Polymer & Material Science: Incorporated into polymer backbones or as a cross-linking agent to impart thermal stability and specific functional properties to advanced polymeric materials.
• Agrochemical Research: Utilized in the development of new herbicides or fungicides, leveraging its heterocyclic structure for bioactivity.
• Analytical Chemistry & Sensor Development: Its ability to bind metals makes it a candidate for designing selective chemical sensors and indicators.

Basic Information

Item	Details
Product Name	1H-Pyrazole-3,5-Dicarboxylic Acid, 1-[(3,5-Dicarboxyphenyl)Methyl]-
CAS No.	2170398-07-7
Molecular Formula	C14H10N2O8
Molecular Weight	334.24 g/mol
Synonyms	1-[(3,5-Dicarboxyphenyl)methyl]-1H-pyrazole-3,5-dicarboxylic acid; 1-(3,5-Dicarboxybenzyl)-1H-pyrazole-3,5-dicarboxylic acid; 3,3',5,5'-Biphenyltetracarboxylic acid, 1H-pyrazole derivative; Pyrazole-3,5-dicarboxylic acid, 1-[(3,5-dicarboxyphenyl)methyl]-; Tetrakis(4-carboxyphenyl)pyrazole derivative (related); PZDC linker (common abbreviation); 1H-Pyrazole-3,5-dicarboxylic acid benzyl derivative
EINECS	Contact for details

Quality Control

Our 1H-Pyrazole-3,5-Dicarboxylic Acid derivative is manufactured under strict quality protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity assessment, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your research or production specifications. Our quality system is designed to support cGMP and ISO standards for reliable, batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.