Description

Chloro[4-(Di-tert-Butylphosphino)-N,n-Dimethylaniline-2-(2'-Aminobiphenyl)]Palladium(II) is a highly specialized, air-stable palladium catalyst belonging to the Buchwald-Hartwig phosphine ligand family. This compound matters for enabling efficient and selective cross-coupling reactions, which are critical for constructing complex molecules in advanced chemical synthesis. It is primarily needed by R&D scientists and process chemists in the pharmaceutical, agrochemical, and advanced materials industries for developing new active ingredients and functional compounds.

Application

• Buchwald-Hartwig Amination: A premier catalyst for C–N bond formation between aryl halides and amines, essential for synthesizing pharmaceutical intermediates and fine chemicals.
• Pharmaceutical Intermediate Synthesis: Key for constructing nitrogen-containing heterocycles and complex amine structures found in active pharmaceutical ingredients (APIs).
• Agrochemical Manufacturing: Used in the synthesis of novel herbicides, fungicides, and insecticides that require specific aryl-amine linkages.
• Material Science Research: Facilitates the creation of organic electronic materials, such as those used in OLEDs, through precise coupling reactions.
• Cross-Coupling Reactions: Effective for other palladium-catalyzed transformations like Suzuki-Miyaura (C–C bond formation) when modified, offering versatility in synthesis routes.
• Process Chemistry & Scale-Up: Its stability makes it suitable for optimizing and scaling laboratory reactions to pilot and manufacturing scales.
• Academic & Industrial R&D: A valuable tool for methodological development and exploring new chemical spaces in catalysis research.

Basic Information

Item	Details
Product Name	Chloro[4-(Di-tert-Butylphosphino)-N,n-Dimethylaniline-2-(2'-Aminobiphenyl)]Palladium(II)
CAS No.	2169976-34-3
Molecular Formula	C28H36ClN2PPd
Molecular Weight	579.42 g/mol
Synonyms	Buchwald Palladium Catalyst G4; Pd-PEPPSI-IPent; Chloro(4-(di-tert-butylphosphino)-N,N-dimethylaniline-2-(2'-aminobiphenyl))palladium(II); Pd-PEPPSI-IPentCl; Palladium(II) chloro[4-(di-tert-butylphosphino)-N,N-dimethylaniline-2-(2'-aminobiphenyl)]-; PEPPSI-IPent Palladium Complex; [Pd(IPent)(Cl)2]; Cross-Coupling Catalyst G4
EINECS	Contact for details

Quality Control

Every batch of our palladium catalysts is produced and tested under strict quality management protocols. We guarantee high catalytic activity and lot-to-lot consistency through advanced analytical techniques. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing parameters such as purity, metal content, and ligand assay. Our quality systems support compliance with cGMP and ISO 9001 standards for customers in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C to maintain long-term stability and prevent decomposition. The container should be kept in a cool, dry, and well-ventilated area, separate from strong oxidizing agents.

Specification

Item	Specification
Appearance	Orange to brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Palladium (Pd) Content	18.0 - 19.0 %
Chloride Content	Meets theoretical value
Solubility	Soluble in common organic solvents (DCM, THF, Toluene)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.