Description

2-Chloro-4-Ethynylbenzoic Acid is a high-value, multi-functional aromatic building block featuring both a carboxylic acid and an ethynyl group. This unique bifunctional structure makes it a critical intermediate for the synthesis of complex molecules in advanced research and development. It is primarily utilized by pharmaceutical, agrochemical, and material science industries for applications such as drug discovery, ligand synthesis, and the creation of novel polymers.

Application

• Pharmaceutical Intermediate: A key synthon in the development of active pharmaceutical ingredients (APIs), particularly for targeted therapies.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and plant growth regulators.
• Material Science Precursor: Serves as a monomer or cross-linking agent in the synthesis of specialty polymers and advanced organic frameworks.
• Ligand and Catalyst Development: The ethynyl group is instrumental for creating novel ligands for catalysis and metal-organic complexes.
• Chemical Biology Probes: Employed in the synthesis of molecular probes and tags for bio-conjugation and imaging studies.
• Academic and R&D: A versatile reagent for organic synthesis and methodology development in university and industrial research laboratories.

Basic Information

Product Name	2-Chloro-4-Ethynylbenzoic Acid
CAS No.	2168559-67-7
Molecular Formula	C9H5ClO2
Molecular Weight	180.59 g/mol
Synonyms	4-Ethynyl-2-chlorobenzoic Acid; 2-Chloro-4-ethynylbenzoic Acid; Benzoic acid, 2-chloro-4-ethynyl-; (4-Ethynyl-2-chlorophenyl)formic Acid
EINECS	Contact for details

Quality Control

Our 2-Chloro-4-Ethynylbenzoic Acid is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and FTIR, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with each shipment and are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.