Description

(2S,3S)-3-(Ethoxycarbonyl)Bicyclo[2.2.2]Oct-5-Ene-2-Carboxylic Acid CAS NO 2166401-97-2 is a high-purity, stereochemically defined bicyclic compound featuring both carboxylic acid and ester functional groups. This unique chiral building block is critical for the synthesis of complex molecules where precise three-dimensional structure dictates biological activity and material properties. It is primarily utilized by research and development teams in the pharmaceutical and advanced materials sectors for creating novel active pharmaceutical ingredients (APIs), ligands, and specialty polymers.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of novel therapeutic agents, particularly for central nervous system (CNS) and antiviral drugs.
• Asymmetric Catalyst Ligand Precursor: Used to synthesize sophisticated chiral ligands for transition metal catalysis, enabling highly enantioselective chemical transformations.
• Advanced Material Monomer: Functions as a building block for the synthesis of specialty polymers with tailored thermal, mechanical, or optical properties.
• Agrochemical Research: Employed in the development of new, stereospecific pesticides and herbicides with improved efficacy and environmental profiles.
• Academic & Industrial R&D: A valuable tool for chemists in academia and contract research organizations (CROs) exploring new synthetic methodologies and molecular architectures.
• Fine Chemical Synthesis: Used in the multi-step synthesis of complex natural products, flavors, and fragrances requiring high stereochemical fidelity.

Basic Information

Product Name	(2S,3S)-3-(Ethoxycarbonyl)Bicyclo[2.2.2]Oct-5-Ene-2-Carboxylic Acid
CAS No.	2166401-97-2
Molecular Formula	C13H16O4
Molecular Weight	236.26 g/mol
Synonyms	(2S,3S)-3-(Ethoxycarbonyl)bicyclo[2.2.2]oct-5-ene-2-carboxylic acid; (2S,3S)-3-(Ethoxycarbonyl)-2-bicyclo[2.2.2]oct-5-ene carboxylic acid; (2S,3S)-Bicyclo[2.2.2]oct-5-ene-2,3-dicarboxylic acid 3-ethyl ester; (2S,3S)-3-Carbethoxybicyclo[2.2.2]oct-5-ene-2-carboxylic acid; (2S,3S)-3-(Ethoxycarbonyl)-2-norbornenecarboxylic acid (derived); Bicyclo[2.2.2]oct-5-ene-2,3-dicarboxylic acid, 3-ethyl ester, (2S,3S)-
EINECS	Contact for details

Quality Control

Our (2S,3S)-3-(Ethoxycarbonyl)Bicyclo[2.2.2]Oct-5-Ene-2-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and process development. Certificates of Analysis (COA) detailing identity, purity, and enantiomeric excess are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere for long-term storage to maintain optimal purity and stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.