Description

(R)-2-(Oxetan-2-Yl)Ethan-1-Amine is a high-purity chiral amine building block featuring a unique oxetane ring system. This compound is of significant value in modern pharmaceutical research and development, particularly for its role in constructing complex molecules with enhanced metabolic stability and improved physicochemical properties. It is primarily sought after by medicinal chemists and process development scientists in the pharmaceutical and biotechnology industries for the synthesis of novel active pharmaceutical ingredients (APIs) and advanced intermediates.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates, especially in oncology, CNS disorders, and antiviral research.
• Proteolysis Targeting Chimera (PROTAC) Development: Used as a linker or warhead component in the design of bifunctional molecules for targeted protein degradation.
• Peptidomimetic Chemistry: Incorporation into peptide backbones to enhance stability against enzymatic degradation and improve membrane permeability.
• Asymmetric Synthesis: Serves as a chiral auxiliary or starting material in stereoselective catalytic reactions to introduce the (R)-configuration into target molecules.
• Bioconjugation: The primary amine functionality allows for conjugation to antibodies, proteins, or other biomolecules for drug delivery applications.
• Material Science Research: Exploration as a monomer or cross-linking agent for specialty polymers with tailored properties.

Basic Information

Product Name	(R)-2-(Oxetan-2-Yl)Ethan-1-Amine
CAS No.	2165965-62-6
Molecular Formula	C6H13NO
Molecular Weight	115.17 g/mol
Synonyms	(R)-2-(2-Oxetanyl)ethylamine; (R)-2-(Oxetan-2-yl)ethanamine; (2R)-2-(Oxetan-2-yl)ethan-1-amine; (R)-2-Oxetan-2-ylethylamine; (R)-Oxetane-2-ethanamine; (R)-Aminoethyloxetane; (R)-2-(2-Oxetanyl)ethanamine
EINECS	Contact for details

Quality Control

Our (R)-2-(Oxetan-2-Yl)Ethan-1-Amine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for prolonged storage or when opening the container to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.