Description

2,2,2-Trifluoro-1-(Pyridin-4-Yl)Ethanamine Dihydrochloride is a high-purity, fluorinated pyridine derivative building block essential for advanced chemical synthesis. This compound matters for its role as a key intermediate in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where the trifluoroethylamine moiety can significantly influence biological activity and metabolic stability. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecules with targeted properties.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of potential drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders, oncology, and anti-infectives.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, where the fluorine atoms can enhance lipophilicity and environmental stability.
• Ligand Synthesis: Serves as a precursor for creating specialized ligands used in catalysis and material science applications.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Fluorinated Compound Library: A valuable component for constructing diverse screening libraries in drug discovery and material science.
• Advanced Material Synthesis: Potential use in the development of fluorinated polymers or liquid crystals with unique properties.

Basic Information

Product Name	2,2,2-Trifluoro-1-(Pyridin-4-Yl)Ethanamine Dihydrochloride
CAS No.	2153472-94-5
Molecular Formula	C7H8F3N2 • 2HCl
Molecular Weight	267.07 g/mol (Free base: 176.15 g/mol)
Synonyms	4-(2,2,2-Trifluoroethyl)pyridin-1-ium Dihydrochloride; 1-(4-Pyridinyl)-2,2,2-trifluoroethanamine Dihydrochloride; 2,2,2-Trifluoro-1-(4-pyridinyl)ethanamine Dihydrochloride; 4-(2-Amino-1,1,1-trifluoroethyl)pyridine Dihydrochloride; 2,2,2-Trifluoro-1-(4-pyridyl)ethylamine Dihydrochloride; 1-(Pyridin-4-yl)-2,2,2-trifluoroethan-1-amine Dihydrochloride
EINECS	Contact for details

Quality Control

Our 2,2,2-Trifluoro-1-(Pyridin-4-Yl)Ethanamine Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to quality supports your R&D and scale-up processes with reliable, high-purity material.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.