Description

Methanesulfonato[2,2'-Bis(Diphenylphosphino)-1,1'-Binaphthyl](2'-Amino-1,1'-Biphenyl-2-Yl)Palladium(II) is a highly specialized, air-stable palladium catalyst featuring a sophisticated bidentate ligand system. This compound is engineered to deliver exceptional catalytic efficiency and selectivity in challenging cross-coupling reactions, which are fundamental to modern synthetic chemistry. It is an indispensable tool for research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors, where precise molecular construction is paramount.

Application

• Pharmaceutical Intermediate Synthesis: A key catalyst for Buchwald-Hartwig amination and Suzuki-Miyaura cross-coupling reactions in the synthesis of complex drug candidates and active pharmaceutical ingredients (APIs).
• Agrochemical Research: Enables the efficient construction of novel heterocyclic compounds and complex molecular architectures for new pesticide and herbicide development.
• Material Science: Facilitates the synthesis of conjugated polymers, organic semiconductors, and specialty monomers for electronic and optoelectronic applications.
• Academic & Industrial R&D: Serves as a premium catalyst for methodological development and the synthesis of novel, structurally demanding organic molecules in laboratory settings.
• Scale-up Process Chemistry: Its stability and defined structure make it suitable for optimization and potential scale-up of catalytic processes from milligram to kilogram scale.

Basic Information

Product Name	Methanesulfonato[2,2'-Bis(Diphenylphosphino)-1,1'-Binaphthyl](2'-Amino-1,1'-Biphenyl-2-Yl)Palladium(II)
CAS No.	2151915-22-7
Molecular Formula	C55H45NO3P2PdS
Molecular Weight	968.33 g/mol
Synonyms	Palladium(II) Methanesulfonate BINAP Amino Biaryl Complex; (2'-Amino[1,1'-biphenyl]-2-yl)[2,2'-bis(diphenylphosphino)-1,1'-binaphthalene]palladium(II) methanesulfonate; Pd(BINAP)(2-NH2-Biphenyl)OMs; Buchwald-Hartwig Catalyst Precursor; BINAP-Pd-Amino Biaryl Complex; Palladium Catalyst with BINAP and 2-Aminobiphenyl Ligand; [Pd(2-NH2C12H8)(BINAP)]OMs
EINECS	Contact for details

Quality Control

Every batch of our palladium catalysts is synthesized and handled under strict inert atmosphere conditions to prevent decomposition. Quality is assured through comprehensive analytical techniques including NMR (¹H, ³¹P), HPLC for purity assessment, and elemental analysis (CHNS). A detailed Certificate of Analysis (COA) documenting identity, purity, and residual solvent content is provided with each shipment to ensure traceability and compliance with your internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store the product under an inert atmosphere (argon or nitrogen) at 2-8°C. The material is easily oxidized and light-sensitive; prolonged exposure to air, moisture, or ambient light should be avoided to maintain catalytic activity.

Specification

Item	Specification
Appearance	Orange to brown solid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Pd Content (ICP-MS)	10.5 - 11.5 %
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.