Description

Neu5Ac Alpha(2-3)Gal Beta(1-4)Glc-β-Pnp is a synthetic, chromogenic substrate designed for the specific detection and study of glycosidase and neuraminidase enzyme activity. This compound is critical for researchers requiring high-purity, well-defined tools to investigate carbohydrate-protein interactions, glycan processing, and viral infection mechanisms. It is primarily utilized by biopharmaceutical R&D teams, diagnostic kit developers, and academic research groups in the fields of glycobiology, virology, and enzymology.

Application

• Enzyme Activity Assays: As a chromogenic substrate for the specific detection and kinetic analysis of neuraminidases (sialidases) and other glycosidases.
• Glycobiology Research: For studying sialic acid linkages, glycan recognition, and carbohydrate-processing pathways in cellular systems.
• Virology and Antiviral Development: Used in high-throughput screening (HTS) platforms to identify and characterize inhibitors of viral neuraminidases (e.g., influenza virus).
• Diagnostic Reagent Manufacturing: Serves as a key component in the formulation of diagnostic kits for enzyme deficiency disorders or pathogen detection.
• Biochemical Tool Development: For the creation of probes and sensors to visualize and quantify enzyme activity in complex biological samples.

Basic Information

Product Name	Neu5Ac Alpha(2-3)Gal Beta(1-4)Glc-β-Pnp
CAS No.	2149582-14-7
Molecular Formula	C31H44N2O21
Molecular Weight	756.69 g/mol
Synonyms	5-N-Acetylneuraminyl-α-(2→3)-D-galactopyranosyl-β-(1→4)-D-glucopyranosyl β-p-nitrophenyl; p-Nitrophenyl 5-acetamido-3,5-dideoxy-D-glycero-α-D-galacto-non-2-ulopyranosidonic acid-(2→3)-β-D-galactopyranosyl-(1→4)-β-D-glucopyranoside; Sialyl Lactose p-Nitrophenyl Glycoside; Neu5Acα2-3Galβ1-4Glcβ-PNP; Chromogenic sialyl lactose substrate; Sialidase substrate; Neuraminidase substrate.
EINECS	Contact for details

Quality Control

Every batch of Neu5Ac Alpha(2-3)Gal Beta(1-4)Glc-β-Pnp is manufactured under strict quality management systems and undergoes comprehensive analytical characterization. Our products are tested to ensure high purity and batch-to-batch consistency, meeting the exacting standards required for research and diagnostic applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0 %
Solubility	Soluble in water, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.