Description

3-(1,1-Difluorobut-3-En-1-Yl)Quinoxaline-2-Ol is a high-value, advanced pharmaceutical intermediate characterized by its unique quinoxaline core and difluorinated alkene side chain. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular frameworks. It is primarily sought by pharmaceutical R&D teams and fine chemical manufacturers engaged in developing next-generation drugs, agrochemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Research: Used in the development of new-generation pesticides and herbicides, leveraging its heterocyclic structure for bioactivity.
• Material Science: Serves as a precursor for organic electronic materials, such as ligands for OLEDs or conductive polymers.
• Chemical Biology: Employed as a probe or scaffold in medicinal chemistry for structure-activity relationship (SAR) studies.
• Academic & Industrial R&D: Utilized in research laboratories for methodological development and exploring new synthetic pathways.
• Custom Synthesis: Foundation for the contract manufacturing of complex, fluorinated organic molecules for specialized client projects.

Basic Information

Product Name	3-(1,1-Difluorobut-3-En-1-Yl)Quinoxaline-2-Ol
CAS No.	2146141-67-3
Molecular Formula	C₁₄H₁₂F₂N₂O
Molecular Weight	262.26 g/mol
Synonyms	2-Hydroxy-3-(1,1-difluorobut-3-en-1-yl)quinoxaline; 3-(1,1-Difluoro-3-buten-1-yl)-2-quinoxalinol; Quinoxalin-2-ol, 3-(1,1-difluorobut-3-en-1-yl)-; 2146141-67-3; DFBQ Intermediate; Difluorobut-3-en-1-yl quinoxalinol derivative
EINECS	Contact for details

Quality Control

Our 3-(1,1-Difluorobut-3-En-1-Yl)Quinoxaline-2-Ol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and consistent chemical identity. Certificates of Analysis (COA) detailing purity, impurities, and full characterization data are provided with every shipment to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.