Description

Methyl 7-Azaspiro[3.5]Nonane-2-Carboxylate Hydrochloride is a high-purity, advanced pharmaceutical intermediate characterized by its unique spirocyclic structure. This compound is of significant value in medicinal chemistry for its role as a key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in the development of new therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of complex bioactive molecules and active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used as a versatile scaffold for constructing spirocyclic compounds in drug discovery programs, especially for neurological targets.
• Process Development & Scale-up: Employed in the optimization and pilot-scale production of new chemical entities (NCEs) for clinical trials.
• Contract Research & Manufacturing (CRAM): Supplied to organizations specializing in custom synthesis and development services for the global pharmaceutical industry.
• Academic Research: Utilized in university and institutional labs for studying structure-activity relationships (SAR) and novel synthetic methodologies.

Basic Information

Product Name	Methyl 7-Azaspiro[3.5]Nonane-2-Carboxylate Hydrochloride
CAS No.	2139294-75-8
Molecular Formula	C10H18ClNO2
Molecular Weight	219.71 g/mol
Synonyms	7-Azaspiro[3.5]nonane-2-carboxylic acid, methyl ester, hydrochloride; Methyl 7-azaspiro[3.5]nonane-2-carboxylate HCl; 2-Carbomethoxy-7-azaspiro[3.5]nonane hydrochloride; 7-Azaspiro[3.5]nonane-2-carboxylic acid methyl ester hydrochloride; Methyl 2-azaspiro[4.4]nonane-7-carboxylate hydrochloride (isomeric); CAS 2139294-75-8
EINECS	Contact for details

Quality Control

Our production of Methyl 7-Azaspiro[3.5]Nonane-2-Carboxylate Hydrochloride adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. All materials are manufactured under a quality system compliant with cGMP principles for pharmaceutical intermediates. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request, detailing purity, identity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.