Description

Benzoic Acid, 2-Amino-4-Bromo-3-Fluoro-5-(Trifluoromethyl)- is a highly functionalized benzoic acid derivative, distinguished by its unique halogen and amino substitution pattern. This compound serves as a critical advanced pharmaceutical intermediate (API) and a versatile building block in modern organic synthesis. It is primarily required by R&D and production teams in the pharmaceutical, agrochemical, and specialty chemical industries for developing novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of complex drug molecules, particularly those targeting neurological disorders and oncology.
• Agrochemical Synthesis: Building block for developing novel herbicides and pesticides with enhanced efficacy and selectivity.
• Ligand & Catalyst Development: Used in the creation of specialized ligands for transition metal catalysis and asymmetric synthesis.
• Material Science Research: Monomer or additive for developing advanced polymers with specific thermal or chemical resistance properties.
• Fluorinated Compound Libraries: Essential for medicinal chemistry research in constructing fluorinated compound libraries for high-throughput screening.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of client-specific target molecules under cGMP conditions.

Basic Information

Product Name	Benzoic Acid, 2-Amino-4-Bromo-3-Fluoro-5-(Trifluoromethyl)-
CAS No.	2134633-62-6
Molecular Formula	C8H4BrF4NO2
Molecular Weight	302.03 g/mol
Synonyms	2-Amino-4-bromo-3-fluoro-5-(trifluoromethyl)benzoic acid; 4-Bromo-3-fluoro-2-amino-5-(trifluoromethyl)benzoic acid; 2-Amino-4-bromo-3-fluoro-α,α,α-trifluoro-m-toluic acid; Benzoic acid, 2-amino-4-bromo-3-fluoro-5-(trifluoromethyl)-; 2134633-62-6; 2-AA-4-Br-3-F-5-CF3-BA (abbrev.)
EINECS	Contact for details

Quality Control

Our Benzoic Acid, 2-Amino-4-Bromo-3-Fluoro-5-(Trifluoromethyl)- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request. We support development and production needs from laboratory to commercial scale with customizable specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Purity (HPLC, Area %)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.