Description

Quinazoline, 7-Bromo-2,4-Dichloro-8-Fluoro-6-(Trifluoromethyl)- is a highly functionalized, multi-halogenated quinazoline derivative designed for advanced chemical synthesis. This compound serves as a critical pharmacophore and versatile building block in medicinal chemistry, enabling the development of novel small-molecule therapeutics. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers engaged in creating targeted inhibitors and other bioactive molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential kinase inhibitors, receptor antagonists, and other targeted therapeutic agents.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Agrochemical Development: Serves as a building block for creating novel active ingredients with herbicidal or fungicidal properties.
• Material Science: Investigated for the synthesis of advanced organic electronic materials and ligands for catalytic systems.
• Chemical Biology: Employed in the development of chemical probes to study specific biological pathways and protein functions.

Basic Information

Product Name	Quinazoline, 7-Bromo-2,4-Dichloro-8-Fluoro-6-(Trifluoromethyl)-
CAS No.	2134618-53-2
Molecular Formula	C10H2BrCl2F4N2
Molecular Weight	378.94 g/mol
Synonyms	7-Bromo-2,4-dichloro-8-fluoro-6-(trifluoromethyl)quinazoline; 2,4-Dichloro-7-bromo-8-fluoro-6-(trifluoromethyl)quinazoline; 6-(Trifluoromethyl)-7-bromo-2,4-dichloro-8-fluoroquinazoline; Quinazoline, 7-bromo-2,4-dichloro-8-fluoro-6-(trifluoromethyl)-; 2134618-53-2; BDTFQ derivative; Multi-halogenated quinazoline scaffold
EINECS	Contact for details

Quality Control

Our high-purity quinazoline derivatives are manufactured under strict quality management systems. Every batch undergoes comprehensive analytical characterization, including HPLC, NMR, and MS, to confirm identity and purity. A detailed Certificate of Analysis (COA) is provided with each shipment, ensuring full traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong bases and reducing agents. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.