Description

Oxazole, 2,2'-Cyclopentylidenebis[4,5-Dihydro-4,5-Diphenyl-, (4R,4'R,5S,5'S)- is a high-purity, stereochemically defined chiral bis-oxazole compound. This advanced chemical intermediate is valued for its rigid, three-dimensional structure and its role as a key building block in sophisticated organic synthesis. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for applications in asymmetric catalysis and the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral ligand or precursor in the asymmetric synthesis of complex drug molecules, particularly for central nervous system (CNS) and oncology targets.
• Agrochemical Research: Used in the development of novel, stereoselective pesticides and herbicides where specific chirality is essential for bioactivity.
• Catalyst Development: Functions as a core structural component in the design of novel transition metal catalysts for enantioselective transformations.
• Material Science: Investigated as a monomer or additive for creating polymers with specific optical or electronic properties due to its fused ring system.
• Academic & Process Chemistry: Employed in methodological research for new synthetic routes and as a standard for studying stereochemical outcomes.

Basic Information

Product Name	Oxazole, 2,2'-Cyclopentylidenebis[4,5-Dihydro-4,5-Diphenyl-, (4R,4'R,5S,5'S)-
CAS No.	2133827-34-4
Molecular Formula	C39H32N2O2
Molecular Weight	560.69 g/mol
Synonyms	(4R,4'R,5S,5'S)-2,2'-Cyclopentylidenebis(4,5-dihydro-4,5-diphenyloxazole); (4R,4'R,5S,5'S)-Bis(diphenyloxazoline)cyclopentane; Chiral Bis(oxazoline) Ligand; (R,R,S,S)-Cp-Box; (4R,4'R,5S,5'S)-Cyclopentane-1,1-diylbis(4,5-dihydro-4,5-diphenyloxazole); Stereoisomer of Cp-Box Ligand; Chiral C2-Symmetric Ligand; Contact for details on additional trade names.
EINECS	Contact for details

Quality Control

Every batch of this advanced chiral intermediate is produced and analyzed under strict quality systems. We provide comprehensive Certificates of Analysis (COA) that include data for chiral purity (enantiomeric excess), chemical purity, and identity confirmation. Our quality commitment aligns with cGMP principles where applicable, ensuring traceability and consistency for critical R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is light-sensitive (store away from light) and should be handled under an inert atmosphere for long-term storage to prevent potential degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% e.e.
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.