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[1,1'-Binaphthalene]-2,2'-Diol, 5,5',6,6',7,7',8,8'-Octahydro-3,3'-Bis(4-Nitrophenyl)-, (1S)- CAS NO 2129645-35-6


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CAS No.:2129645-35-6

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

[1,1'-Binaphthalene]-2,2'-Diol, 5,5',6,6',7,7',8,8'-Octahydro-3,3'-Bis(4-Nitrophenyl)-, (1S)- is a sophisticated chiral ligand and building block of significant interest in advanced organic synthesis. Its value lies in its highly functionalized, atropisomeric binaphthyl core, which is crucial for inducing stereoselectivity in catalytic reactions. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel asymmetric catalysts, chiral auxiliaries, and complex molecular architectures.

Application

  • As a chiral ligand in asymmetric metal-catalyzed reactions, including hydrogenation, cross-coupling, and C-H activation.
  • As a key intermediate in the synthesis of complex natural products and pharmaceuticals requiring high enantiomeric purity.
  • In the development of organocatalysts and molecular recognition systems due to its pre-organized, sterically demanding structure.
  • For research into advanced materials, such as chiral polymers and liquid crystals, where its rigid scaffold can impart specific optical properties.
  • As a building block for constructing supramolecular assemblies and sensors designed for enantioselective detection.

Basic Information

Product Name [1,1'-Binaphthalene]-2,2'-Diol, 5,5',6,6',7,7',8,8'-Octahydro-3,3'-Bis(4-Nitrophenyl)-, (1S)-
CAS No. 2129645-35-6
Molecular Formula C32H28N2O6
Molecular Weight 536.58 g/mol
Synonyms (1S)-5,5',6,6',7,7',8,8'-Octahydro-3,3'-bis(4-nitrophenyl)-[1,1'-binaphthalene]-2,2'-diol; (S)-H8-BINOL-3,3'-dinitrophenyl derivative; (S)-Octahydro-3,3'-dinitrophenyl-BINOL; (S)-3,3'-Bis(4-nitrophenyl)-5,5',6,6',7,7',8,8'-octahydro-1,1'-bi-2-naphthol; Chiral Dinitrophenyl-Substituted H8-BINOL Ligand
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Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Every batch is characterized using advanced analytical techniques to confirm identity, purity, and enantiomeric excess. Certificates of Analysis (COA) are available upon request, detailing specifications such as chiral purity (HPLC), chemical purity (HPLC/NMR), and residual solvent content.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C or as specified on the label or COA. This compound is light-sensitive and easily oxidized; prolonged exposure to air, light, or elevated temperatures should be avoided to maintain stability and purity.

Specification

Item Specification
Appearance Yellow to orange solid
Identification (IR) Conforms to structure
Identification (HPLC) Conforms to reference
Purity (HPLC) ≥ 97.0%
Chiral Purity (HPLC) ≥ 99.0% ee
Water Content (KF) ≤ 0.5%
Residual Solvents (GC) Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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