Description

Boc-Aminooxy-Ethyl-Ss-Propanol is a specialized protected aminooxy derivative used as a key intermediate in advanced organic synthesis. This compound matters for its role in constructing complex molecules, particularly through oxime ligation and bioconjugation strategies, enabling precise chemical modifications. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel therapeutics, diagnostics, and bioconjugates.

Application

• Bioconjugation Reagent: For site-specific labeling of proteins, antibodies, and peptides via oxime bond formation.
• Pharmaceutical Intermediate: In the synthesis of active pharmaceutical ingredients (APIs) and prodrugs requiring aminooxy functionality.
• Linker Chemistry: Serves as a versatile building block for creating cleavable or stable linkers in antibody-drug conjugates (ADCs).
• Polymer Modification: For the functionalization of polymers and surfaces to introduce reactive aminooxy groups.
• Carbohydrate Chemistry: Used in the synthesis of glycoconjugates and neoglycoproteins.
• Material Science: As a precursor for creating functionalized materials with specific surface properties.
• Chemical Biology Probes: For the development of probes to study biological processes and interactions.
• Cross-linking Agent: In the preparation of hydrogels and cross-linked biomaterials.

Basic Information

Product Name	Boc-Aminooxy-Ethyl-Ss-Propanol
CAS No.	2128735-21-5
Molecular Formula	C11H23NO5S
Molecular Weight	281.37 g/mol
Synonyms	tert-Butyl N-(2-{[2-(hydroxy)ethyl]sulfanyl}ethoxy)carbamate; 2-({2-[(tert-Butoxycarbonyl)amino]oxy}ethyl)sulfanyl)ethan-1-ol; Boc-Aminooxyethyl Thioethyl Alcohol; Boc-protected Aminooxy Ethyl Sulfanyl Ethanol; Aminooxy-PEG2-Thiol (Boc protected); (Boc-Aminooxy)ethyl 2-hydroxyethyl sulfide
EINECS	Contact for details

Quality Control

Our Boc-Aminooxy-Ethyl-Ss-Propanol is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards for fine chemical intermediates, and specifications can be tailored to meet specific research or cGMP starting material requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C under an inert atmosphere (e.g., nitrogen or argon) due to its hygroscopic and easily oxidized nature. Allow the container to reach room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.