Description

(3S,6R)-6-Methylpiperidin-3-Ol Hydrochloride is a high-purity chiral piperidine derivative, serving as a critical building block in advanced organic synthesis. Its defined stereochemistry and hydrochloride salt form offer enhanced stability and solubility, making it invaluable for the development of stereospecific pharmaceuticals. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in areas like neurology and metabolic disease research. CAS NO 2126144-54-3.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new drug candidates, especially for central nervous system (CNS) targets.
• Asymmetric Synthesis: Used as a chiral auxiliary or precursor in catalytic asymmetric reactions to induce stereoselectivity.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and lead optimization for novel therapeutic agents.
• Chemical Biology Probes: Serves as a scaffold for developing molecular probes to study enzyme function and biological pathways.
• Process Chemistry: Investigated for scalable synthesis routes in the pilot-scale and commercial manufacturing of complex molecules.

Basic Information

Product Name	(3S,6R)-6-Methylpiperidin-3-Ol Hydrochloride
CAS No.	2126144-54-3
Molecular Formula	C6H14ClNO
Molecular Weight	151.64 g/mol
Synonyms	(3S,6R)-6-Methyl-3-piperidinol hydrochloride; (3S,6R)-6-Methylpiperidin-3-ol HCl; 6-Methyl-3-piperidinol hydrochloride, (3S,6R)-; 3-Piperidinol, 6-methyl-, hydrochloride, (3S,6R)-; (3S,6R)-3-Hydroxy-6-methylpiperidine hydrochloride
EINECS	Contact for details

Quality Control

Our (3S,6R)-6-Methylpiperidin-3-Ol Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the stringent requirements for pharmaceutical R&D. A detailed Certificate of Analysis (COA) providing full specifications, including assay, enantiomeric excess, and impurity profile, is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.