Description

trans-2-Fluorocyclopentan-1-Amine Hcl is a high-purity, fluorinated chiral amine building block of significant interest in advanced organic synthesis. This compound matters as a key intermediate for constructing complex molecular architectures, particularly in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for applications in medicinal chemistry, process development, and asymmetric synthesis.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the research and development of new drug candidates, particularly in central nervous system (CNS) and metabolic disease targets.
• Agrochemical Synthesis: Used in the creation of advanced, fluorinated pesticides and herbicides, where the fluorine atom can enhance biological activity and stability.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis to create enantiomerically pure compounds.
• Peptidomimetics Research: Incorporated into peptide backbones to modulate conformation, metabolic stability, and bioavailability in drug discovery.
• Chemical Biology Probes: Utilized in the synthesis of molecular probes for studying enzyme mechanisms and biological pathways.
• Material Science: Potential monomer or additive for specialty polymers with unique properties derived from its fluorinated cyclopentane structure.

Basic Information

Product Name	trans-2-Fluorocyclopentan-1-Amine Hcl
CAS No.	2125943-82-8
Molecular Formula	C5H11ClFN
Molecular Weight	139.60 g/mol
Synonyms	trans-2-Fluorocyclopentanamine hydrochloride; (1R,2S)-2-Fluorocyclopentan-1-amine hydrochloride; (1S,2R)-2-Fluorocyclopentan-1-amine hydrochloride; 2-Fluorocyclopentan-1-amine hydrochloride (trans); trans-1-Amino-2-fluorocyclopentane hydrochloride; Fluorocyclopentylamine HCl (trans); FCYPA-HCl; trans-2-F-CPA HCl
EINECS	Contact for details

Quality Control

Our trans-2-Fluorocyclopentan-1-Amine Hcl is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure it meets the high standards required for research and commercial synthesis. Certificates of Analysis (COA) with detailed chromatographic data (HPLC, GC) and spectroscopic characterization are provided to guarantee batch-to-batch consistency and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere after opening to maintain stability and purity. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (trans isomer)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.