Description

5-Bromo-3-(n-Propylaminocarbonyl)Phenylboronic Acid is a sophisticated bifunctional organoboron building block designed for advanced synthetic chemistry. Its core value lies in enabling the precise construction of complex molecular architectures through reliable cross-coupling reactions, such as the Suzuki-Miyaura reaction. This high-purity intermediate is essential for researchers and process chemists in the pharmaceutical and agrochemical industries developing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting CNS disorders, oncology, and metabolic diseases.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging its boronic acid functionality for carbon-carbon bond formation.
• Material Science Research: Serves as a precursor for creating functionalized polymers, liquid crystals, and organic electronic materials via its reactive sites.
• Chemical Biology & Probe Development: Employed in the synthesis of molecular probes and bioconjugates for studying biological pathways and target engagement.
• Cross-Coupling Reactions: Primarily utilized in palladium-catalyzed Suzuki-Miyaura couplings to introduce the substituted phenyl moiety into more complex molecules.
• Library Synthesis for Drug Discovery: Enables the rapid generation of diverse compound libraries for high-throughput screening in early-stage drug discovery programs.

Basic Information

Product Name	5-Bromo-3-(n-Propylaminocarbonyl)Phenylboronic Acid
CAS No.	2121512-78-3
Molecular Formula	C10H13BBrNO3
Molecular Weight	286.93 g/mol
Synonyms	5-Bromo-3-(propylcarbamoyl)phenylboronic Acid; [5-Bromo-3-(propylaminocarbonyl)phenyl]boronic Acid; 3-Borono-5-bromo-N-propylbenzamide; B-[5-Bromo-3-[(propylamino)carbonyl]phenyl]boronic Acid; 5-Bromo-N-propyl-3-boronobenzamide; (5-Bromo-3-propylcarbamoylphenyl)boronic Acid; 2121512-78-3
EINECS	Contact for details

Quality Control

Every batch of 5-Bromo-3-(n-Propylaminocarbonyl)Phenylboronic Acid is manufactured under strict quality management systems and undergoes comprehensive analytical testing. We ensure compliance with stringent internal specifications suitable for research and commercial-scale synthesis. A detailed Certificate of Analysis (COA) providing purity, identity, and impurity profiles via techniques like HPLC, NMR, and IR is provided with each shipment to guarantee reproducible performance in your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.