Description

Propargyl-Peg10-Amine is a heterobifunctional polyethylene glycol (PEG) derivative featuring a terminal propargyl group and a primary amine. This compound is a critical building block in bioconjugation and click chemistry, enabling the precise, high-yield attachment of biomolecules, polymers, and other functional moieties. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and advanced materials sectors who require reliable, high-purity linkers for developing novel therapeutics, diagnostics, and functionalized surfaces.

Application

• Bioconjugation reagent for attaching peptides, proteins, and oligonucleotides via copper-catalyzed azide-alkyne cycloaddition (CuAAC).
• Surface functionalization of nanoparticles, quantum dots, and biosensors to introduce amine-reactive sites.
• Intermediate in the synthesis of antibody-drug conjugates (ADCs) and other targeted drug delivery systems.
• Polymer modification to create amine-terminated, water-soluble PEG derivatives for hydrogel formation.
• Crosslinking agent for the preparation of biocompatible scaffolds and matrices in tissue engineering.
• Tool compound in chemical biology for labeling and tracking biomolecules in cellular assays.

Basic Information

Product Name	Propargyl-Peg10-Amine
CAS No.	2112737-25-2
Molecular Formula	C25H49NO11
Molecular Weight	539.66 g/mol
Synonyms	Propargyl-PEG10-amine; 2,5,8,11,14,17,20,23,26,29-Decaoxahentriacont-30-yn-31-amine; α-Propargyl-ω-amino PEG10; Propargyl-PEG10-NH2; Propargyl-PEG500-amine; Propargyl-PEG10-amine; 1-Amino-3,6,9,12,15,18,21,24,27,30-decaoxadotriacont-31-yne; Propargyl-PEG10 Amine
EINECS	Contact for details

Quality Control

Our Propargyl-Peg10-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and consistent performance for sensitive bioconjugation applications. Certificates of Analysis (COA) detailing purity, identity, and functional group integrity are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C under an inert atmosphere (e.g., nitrogen or argon) due to its hygroscopic and easily oxidized nature. Allow the sealed container to reach room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Amine Value (Titration)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.