Description

(R)-2-Amino-3-(4-Fluorophenyl)Propan-1-Ol Hydrochloride is a high-purity chiral building block and pharmaceutical intermediate of significant commercial importance. Its value lies in its defined stereochemistry and functional groups, which are critical for synthesizing active pharmaceutical ingredients (APIs) with specific biological activity. This compound is essential for research and development chemists and manufacturers in the pharmaceutical and fine chemical industries, particularly those focused on central nervous system (CNS) and cardiovascular therapeutics.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of novel drug candidates, particularly β-adrenergic blockers and other neuroactive compounds.
• Active Pharmaceutical Ingredient (API) Development: Serves as a precursor in the research and production of enantiomerically pure APIs.
• Asymmetric Synthesis: Used as a starting material or chiral auxiliary in catalytic and stoichiometric asymmetric reactions.
• Biochemical Research: Employed in studies of enzyme inhibition, receptor binding, and metabolic pathways due to its structural similarity to natural amino alcohols.
• Fine Chemical Synthesis: A versatile building block for creating complex, fluorinated organic molecules for advanced material science.

Basic Information

Product Name	(R)-2-Amino-3-(4-Fluorophenyl)Propan-1-Ol Hydrochloride
CAS No.	2102410-90-0
Molecular Formula	C9H13ClFNO
Molecular Weight	205.66 g/mol
Synonyms	(R)-1-(4-Fluorophenyl)-3-amino-2-propanol hydrochloride; (R)-3-Amino-1-(4-fluorophenyl)-2-propanol hydrochloride; (R)-2-Amino-3-(4-fluorophenyl)-1-propanol hydrochloride; (R)-4-Fluoro-β-hydroxybenzeneethanamine hydrochloride; (R)-Norfenefrine Impurity Hydrochloride; (R)-Arterenol analog hydrochloride; (1R)-2-Amino-3-(4-fluorophenyl)propan-1-ol hydrochloride
EINECS	Contact for details

Quality Control

Our (R)-2-Amino-3-(4-Fluorophenyl)Propan-1-Ol Hydrochloride is manufactured under strict quality management systems. Each batch is subjected to rigorous analytical testing, including chiral purity analysis, to ensure it meets the high standards required for pharmaceutical R&D and cGMP applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, chiral excess, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere or in a desiccator after opening to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (Chiral HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.