Description

6-Bromo-8-Iodoquinolin-2(1H)-One is a high-purity, multi-halogenated quinolinone derivative, serving as a critical advanced intermediate in modern synthetic chemistry. Its unique halogen substitution pattern makes it a valuable scaffold for constructing complex molecules with tailored electronic and steric properties. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors and other heterocyclic-based therapeutics.
• Agrochemical Research: Used in the development of new pesticides and herbicides, where the quinolinone core provides a versatile platform for bioactivity.
• Material Science Precursor: Serves as a starting material for creating organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components for organic light-emitting diodes (OLEDs).
• Chemical Biology Probe: Employed in the design and synthesis of molecular probes for studying biological pathways and protein interactions.
• Cross-Coupling Reactions: The bromo and iodo substituents make it an excellent substrate for versatile palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) to create diverse compound libraries.
• Academic & Contract Research: Essential reagent for university laboratories and contract research organizations (CROs) engaged in novel heterocyclic chemistry and method development.

Basic Information

Product Name	6-Bromo-8-Iodoquinolin-2(1H)-One
CAS No.	2101658-56-2
Molecular Formula	C9H5BrINO
Molecular Weight	349.95 g/mol
Synonyms	6-Bromo-8-iodo-1,2-dihydroquinolin-2-one; 6-Bromo-8-iodoquinolin-2-ol; 2(1H)-Quinolinone, 6-bromo-8-iodo-; 6-Bromo-8-iodo-2-quinolone; 6-Bromo-8-iodo-2(1H)-quinolinone; 8-Iodo-6-bromoquinolin-2(1H)-one
EINECS	Contact for details

Quality Control

Our 6-Bromo-8-Iodoquinolin-2(1H)-One is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity verification and NMR/LC-MS for structural confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing batch-specific results are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.