Description

7-Fluoro-2,3,4,5-Tetrahydro-1H-Benzo[C]Azepine Hydrochloride is a high-purity, advanced pharmaceutical intermediate belonging to the benzazepine class of compounds. This compound is of significant value for medicinal chemistry research and development, particularly in the synthesis of novel active pharmaceutical ingredients (APIs) targeting central nervous system (CNS) disorders. It is primarily sought by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in the development of new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel benzazepine-based drug candidates for neurological and psychiatric conditions.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs to develop new therapeutic molecules.
• Preclinical Development: Serves as a critical raw material for producing compounds required for pharmacological profiling, toxicology studies, and early-stage formulation development.
• Reference Standard: Can be utilized as a high-purity analytical standard for method development and quality control in API manufacturing.
• Chemical Biology Probes: Useful for creating specialized probes to study biological pathways and receptor interactions in research settings.

Basic Information

Product Name	7-Fluoro-2,3,4,5-Tetrahydro-1H-Benzo[C]Azepine Hydrochloride
CAS No.	2097938-75-3
Molecular Formula	C10H11FN•HCl
Molecular Weight	199.66 g/mol (Free base: 163.20 g/mol)
Synonyms	7-Fluoro-2,3,4,5-tetrahydro-1H-3-benzazepine hydrochloride; 1H-3-Benzazepine, 7-fluoro-2,3,4,5-tetrahydro-, hydrochloride; 7-Fluoro-1,2,4,5-tetrahydro-3H-3-benzazepine hydrochloride; 7-Fluoro-2,3,4,5-tetrahydro-1H-benzo[c]azepine HCl; 7-Fluoro-3-benzazepine hydrochloride; 2097938-75-3
EINECS	Contact for details

Quality Control

Our 7-Fluoro-2,3,4,5-Tetrahydro-1H-Benzo[C]Azepine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and KF titration for moisture content, to ensure it meets the stringent requirements for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.