Description

4-Fluorobenzylamine Hydroiodide is an organofluorine building block and a key intermediate in advanced organic synthesis. This compound is valued for its role in introducing the 4-fluorobenzyl moiety, a crucial structural motif in medicinal chemistry and materials science. It is primarily utilized by researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of fluorinated drug candidates targeting CNS disorders, oncology, and infectious diseases.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluorine atom enhances biological activity, stability, and metabolic properties.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and catalysts used in asymmetric synthesis and cross-coupling reactions.
• Material Science Research: Employed in the synthesis of fluorinated polymers, liquid crystals, and other advanced materials with unique electronic and surface properties.
• Peptide Modification: Used to incorporate fluorinated aromatic groups into peptides and peptidomimetics, altering their pharmacokinetic profiles and binding affinities.
• Chemical Biology Probes: Acts as a starting material for synthesizing fluorescent tags and molecular probes for imaging and diagnostic applications.

Basic Information

Product Name	4-Fluorobenzylamine Hydroiodide
CAS No.	2097121-30-5
Molecular Formula	C7H9FIN
Molecular Weight	253.06 g/mol
Synonyms	(4-Fluorophenyl)methanamine Hydroiodide; 4-Fluorobenzylammonium Iodide; 1-(4-Fluorophenyl)methanamine Hydroiodide; p-Fluorobenzylamine Hydroiodide; 4-Fluoro-BnNH2·HI; Benzenemethanamine, 4-fluoro-, hydroiodide; 4-Fluorobenzylamine Hydroiodide Salt; 4-FBA·HI
EINECS	Contact for details

Quality Control

Our 4-Fluorobenzylamine Hydroiodide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and FTIR, to ensure high chemical purity and identity. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications. We support cGMP and ISO 9001 standards for pharmaceutical and research-grade intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.