Description

Ethyl 3-(Hydroxymethyl)Bicyclo[1.1.1]Pentane-1-Carboxylate is a high-value, synthetically challenging bicyclic building block of significant interest in advanced organic synthesis. Its unique [1.1.1]propellane-derived scaffold provides a rigid, three-dimensional structure that is crucial for modulating the physicochemical properties of target molecules. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the discovery of novel bioactive compounds.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly for creating sp3-rich, three-dimensional fragments to improve drug-like properties.
• Agrochemical Research: Used in developing new active ingredients for crop protection, where its rigid structure can enhance binding affinity and environmental stability.
• Material Science: Acts as a monomer or cross-linking agent for creating polymers with unique mechanical and thermal properties due to its strained bicyclic core.
• Chemical Biology Probe Development: Employed as a scaffold for designing molecular probes and tools to study biological systems and enzyme functions.
• Ligand and Catalyst Design: Utilized in organometallic chemistry for constructing sophisticated ligands that can modulate metal catalyst activity and selectivity.

Basic Information

Product Name	Ethyl 3-(Hydroxymethyl)Bicyclo[1.1.1]Pentane-1-Carboxylate
CAS No.	2095495-83-1
Molecular Formula	C9H14O3
Molecular Weight	170.21 g/mol
Synonyms	Ethyl 3-(hydroxymethyl)bicyclo[1.1.1]pentane-1-carboxylate; 1-Carboxy-3-(hydroxymethyl)bicyclo[1.1.1]pentane ethyl ester; Bicyclo[1.1.1]pentane-1-carboxylic acid, 3-(hydroxymethyl)-, ethyl ester; 3-(Hydroxymethyl)bicyclo[1.1.1]pentane-1-carboxylic Acid Ethyl Ester; [1.1.1]Propellane derivative, ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 3-(Hydroxymethyl)Bicyclo[1.1.1]Pentane-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific customer requirements for research and cGMP applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed under an inert atmosphere for long-term storage to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0% (Standard Grade)
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.